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Effects of ethacrynic acid on Schlemm's canal inner wall and outflow facility in human eyes.

Author: ColomaF M, EthierC R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The relationship between inner wall pore characteristics of Schlemm's canal and aqueous outflow facility was investigated in human eyes.
Paper Details　
Original Abstract of the Article :
The role of the inner wall of Schlemm's canal in determining aqueous outflow facility is poorly understood. To quantify the relationship between inner wall pore characteristics and aqueous outflow facility in human eyes, both control eyes and eyes in which facility had been pharmacologically increas...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/10359344

データ提供：米国国立医学図書館（NLM）

Ethacrynic Acid: Its Impact on Aqueous Outflow Facility

The [aqueous outflow facility] in the eye is crucial for maintaining [intraocular pressure] and preventing [glaucoma]. This study investigates the role of [the inner wall of Schlemm's canal] in determining [aqueous outflow facility], examining the effects of [ethacrynic acid (ECA) infusion] on [pore characteristics and outflow facility] in [human eyes]. Researchers compared [control eyes] with [eyes treated with ECA], providing insights into the mechanisms by which [ECA] influences [aqueous outflow facility].

Ethacrynic Acid: A Potential Tool for Glaucoma Management

This study revealed a relationship between [inner wall pore characteristics] and [aqueous outflow facility], suggesting that [ECA] can effectively increase [aqueous outflow facility] by modifying [pore characteristics] in [Schlemm's canal]. These findings suggest that [ECA] may have potential as a [therapeutic agent] for managing [glaucoma], a condition characterized by [elevated intraocular pressure].

Maintaining Eye Health: A Focus on Aqueous Outflow

Understanding the [mechanisms of aqueous outflow] is crucial for [maintaining eye health] and preventing [glaucoma]. This study provides valuable information about the [role of Schlemm's canal] in [aqueous outflow] and the potential for [medications like ECA] to influence this process. Maintaining [healthy intraocular pressure] is essential for protecting our vision, and research like this helps us better understand the complex mechanisms involved in [eye health].

Dr. Camel's Conclusion

Just as a camel's vision is crucial for navigating the desert, our eyes are essential for experiencing the world. This study sheds light on the intricate mechanisms of [aqueous outflow], providing valuable insights into maintaining [eye health] and preventing [glaucoma]. By understanding these processes, we can continue to explore new avenues for protecting our precious vision.

Date :
  1. Date Completed 1999-06-17
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

10359344

DOI: Digital Object Identifier

10359344

Related Literature

Article Analysis
・Effects of ethacrynic acid
SNS
PICO Info
in preparation
Languages

English

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