The gastroduodenal effects of buffered aspirin, carprofen, and etodolac in healthy dogs.

Author: DuncanR B, GimbertK, JohnstonS A, LeibM S, MariniM, ReimerD C, ReimerM E

Paper Details 
Original Abstract of the Article :
Twenty-four healthy mixed-breed dogs were divided into 4 groups. Group 1 received a placebo p.o. q12h, group 2 received an average of 16.5 (15.1-17.8) mg/kg buffered aspirin p.o. q12h, group 3 received an average of 2.2 (2.0-2.4) mg/kg carprofen p.o. q12h, and group 4 received an average of 12.8 (11...See full text at original site
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引用元:
https://doi.org/10.1892/0891-6640(1999)013<0472:tgeoba>2.3.co;2

データ提供:米国国立医学図書館(NLM)

Aspirin, Carprofen, and Etodolac: A Gastroduodenal Odyssey in Canine Companions

Veterinary medicine is a vast and complex field, with a constant need for understanding the effects of various medications on our animal friends. This study, a veritable expedition into the canine gastrointestinal tract, examines the effects of buffered aspirin, carprofen, and etodolac on the gastroduodenal health of healthy dogs. The study employed a rigorous experimental design, dividing 24 dogs into four groups and closely monitoring them over 28 days. The findings provide crucial insights into the potential gastrointestinal effects of these medications, guiding veterinary practitioners in their decision-making.

Aspirin: A Potential Source of Gastroduodenal Distress

The study revealed that aspirin, a common pain reliever, was associated with the development of erosions and submucosal hemorrhages in the dogs. This finding suggests that aspirin should be administered with caution in dogs, especially those with pre-existing gastrointestinal conditions.

Healthy Paws, Healthy Choices

This research underscores the importance of responsible medication use in our furry companions. Just as we pay attention to our own health, it's vital to be aware of the potential side effects of medications, especially those that may impact the delicate balance of the gastrointestinal system.

Dr.Camel's Conclusion

This study provides valuable insights into the gastrointestinal impact of common medications in dogs. Much like navigating a desert landscape, understanding the potential risks and benefits of these drugs is crucial for ensuring the well-being of our canine friends.

Date :
  1. Date Completed 1999-11-23
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

10499732

DOI: Digital Object Identifier

10.1892/0891-6640(1999)013<0472:tgeoba>2.3.co;2

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