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A comparison of the residual effects of zaleplon and zolpidem following administration 5 to 2 h before awakening.

Author: CevallosW, DanjouP, FruncilloR, MartinP, PatyI, UnruhM, WorthingtonP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Zaleplon 10 mg is free of residual hypnotic or sedative effects when administered nocturnally as little as 2 hours before waking, while zolpidem 10 mg shows significant residual effects up to 5 hours after administration.
Paper Details　
Original Abstract of the Article :
AIMS: To compare the duration of the residual hypnotic and sedative effects of zaleplon with those of zolpidem and placebo following nocturnal administration at various times before morning awakening. METHODS: Zaleplon 10 mg, zolpidem 10 mg, or placebo was administered double-blind to 36 healthy su...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2125.1999.00024.x

データ提供：米国国立医学図書館（NLM）

The Sleep Sleuth: A Comparison of Zaleplon and Zolpidem's Residual Effects

Sleep is a vital oasis in the desert of our daily lives, and finding the right sleep aid can be like searching for a hidden spring. This study compares the residual effects of two popular sleep medications, zaleplon and zolpidem, on the cognitive and physical well-being of individuals. The researchers meticulously evaluated the effects of these medications on various cognitive functions, such as attention, memory, and reaction time, after administration at different times before waking up.

A Tale of Two Sleep Aids: Zaleplon's Lasting Benefits

The results of this study reveal a clear distinction between the two sleep aids. Zaleplon, like a gentle desert breeze, exhibited minimal to no residual effects on cognitive function, even when administered as little as two hours before waking up. In contrast, zolpidem, like a lingering desert mirage, showed significant residual effects on cognitive function up to five hours after administration. These findings highlight the importance of choosing the right sleep aid to ensure a clear-headed and productive morning.

A Guide to Choosing the Right Sleep Companion

For those who value a clear mind and optimal cognitive performance in the morning, zaleplon appears to be a more advantageous sleep aid. By selecting the right sleep medication, individuals can minimize the possibility of sleep inertia and ensure a smooth transition from sleep to their daily activities. This study serves as a valuable guide for individuals seeking to improve their sleep quality and optimize their cognitive function.

Dr.Camel's Conclusion

The choice of a sleep aid is a crucial one, as it can significantly impact our cognitive function and overall well-being. This study provides valuable insights into the comparative effects of zaleplon and zolpidem, highlighting zaleplon's superior ability to minimize residual sleep effects and enhance morning alertness. Just as a wise desert traveler selects the right camel for their journey, choosing the right sleep aid is essential for a restful sleep and a bright, clear-headed morning.

Date :
  1. Date Completed 1999-11-16
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

10510148

DOI: Digital Object Identifier

10.1046/j.1365-2125.1999.00024.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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