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Dose-ranging study of a new steroid for asthma: mometasone furoate dry powder inhaler.
Author: BerkowitzR B, BernsteinD I, ChervinskyP, CussF M, DvorinD J, FinnA F, GrossG N, HarrisonJ E, KaretzkyM, KempJ P, LaforceC, LumryW, MendelsonL M, NelsonH, NolopK B, PearlmanD, RachelefskyG, RatnerP, RepsherL, SegalA T, SelnerJ C, SettipaneG A, WandererA
Original Abstract of the Article :
A new formulation of mometasone furoate (MF) for administration by dry powder inhaler (DPI) was evaluated for the treatment of asthma. A 12-week, double-blind, placebo-controlled dose-ranging study compared the efficacy and safety of three doses of MF DPI (100, 200 and 400 mcg b.i.d) with beclometha...See full text at original site
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引用元:
https://doi.org/10.1016/s0954-6111(99)90099-9
データ提供:米国国立医学図書館(NLM)
Mometasone Furoate Inhaler: A Breath of Fresh Air for Asthma
This research focuses on the efficacy of mometasone furoate (MF) dry powder inhaler (DPI) for asthma treatment. The study employed a 12-week double-blind, placebo-controlled dose-ranging trial to compare the effectiveness of various MF DPI doses with beclomethasone dipropionate (BDP) administered via a metered dose inhaler. The primary endpoint was forced expiratory volume in 1 second (FEV1), a key measure of lung function. The results indicate that MF DPI significantly improved FEV1 and other pulmonary function measures in patients with asthma. The study also revealed that the optimal dose for MF DPI in this study was 200 mcg b.i.d. (twice daily).
MF DPI: A Promising Option for Asthma Management
The study's findings suggest that MF DPI, at an optimal dose of 200 mcg b.i.d., can effectively improve lung function and alleviate asthma symptoms. This could be a valuable treatment option for individuals with moderate persistent asthma, offering a more effective and well-tolerated alternative to other inhalers. The results show that MF DPI could be a valuable tool for managing asthma, potentially improving the quality of life for individuals living with this condition.
Breathing Easy: Harnessing the Power of Inhalation Therapy
Imagine a vast desert landscape, with the air carrying healing properties. That's what MF DPI represents – a targeted delivery of medication directly to the lungs, potentially offering significant relief for individuals struggling with asthma. This research underscores the importance of exploring innovative inhalation therapies for managing respiratory diseases, potentially leading to better treatment outcomes and improved quality of life for patients. We need to remember that just as the desert has its own unique remedies, medical advancements are constantly unveiling new ways to address health challenges.
Dr.Camel's Conclusion
MF DPI demonstrates the potential of personalized medicine in asthma management. The study's findings highlight the importance of finding the optimal dose for individual patients, ensuring maximum efficacy and minimizing potential side effects. It's like finding the perfect oasis in a vast desert – a place of respite and healing. This research is a testament to the ongoing quest for better treatments for asthma, and we can anticipate further advancements in the field of inhalation therapy.
Date :
- Date Completed 1999-12-22
- Date Revised 2019-09-05
Further Info :
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