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The design of a prospective study of Pravastatin in the Elderly at Risk (PROSPER). PROSPER Study Group. PROspective Study of Pravastatin in the Elderly at Risk.

Author: BlauwG J, BollenE L, BuckleyB M, CobbeS M, FordI, GawA, HylandM, JukemaJ W, LagaayA M, MacfarlaneP W, MeindersA E, MurphyM B, PackardC J, PerryI J, ShepherdJ, StottD J, SweeneyB J, TwomeyC, WestendorpR G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The PROSPER study is investigating the effectiveness of pravastatin in reducing major vascular events in elderly individuals with pre-existing vascular disease or high risk of developing it.
Paper Details　
Original Abstract of the Article :
The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) is a randomized, double-blind, placebo-controlled trial designed to test the hypothesis that treatment with pravastatin will diminish risk of subsequent major vascular events in a cohort of men and women (70 to 82 years old) with ...See full text at original site
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引用元：
https://doi.org/10.1016/s0002-9149(99)00533-0

データ提供：米国国立医学図書館（NLM）

Preventing the Sands of Time: Pravastatin and the Elderly at Risk

As we age, our bodies become more susceptible to heart disease and other vascular problems. Imagine aging as a journey across a vast desert, where the sands of time can erode our health. This study investigates the potential benefits of pravastatin, a cholesterol-lowering medication, in reducing the risk of major vascular events in elderly individuals. The researchers conducted a large randomized, double-blind, placebo-controlled trial involving 5,804 participants aged 70 to 82 years with preexisting vascular disease or a high risk of developing it. The study aims to determine if pravastatin can help prevent cardiovascular events and improve overall health in this vulnerable population.

Protecting the Elderly from Vascular Threats

This study highlights the importance of managing cardiovascular risk in the elderly population. The researchers hope to demonstrate the potential of pravastatin in reducing the risk of heart disease and stroke, contributing to better health outcomes for this vulnerable group.

A Proactive Approach to Cardiovascular Health

The study emphasizes the importance of preventive measures for cardiovascular health, particularly in the elderly. Maintaining a healthy lifestyle, including regular exercise, a balanced diet, and regular medical checkups, is essential for reducing cardiovascular risks.

Dr.Camel's Conclusion

This study is like a seasoned caravan leader, guiding us through the challenges of aging. The research is exploring the potential of pravastatin to protect the elderly from the threats of vascular disease, ensuring a smoother and healthier journey through the sands of time.

Date :
  1. Date Completed 1999-12-02
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

10569329

DOI: Digital Object Identifier

10.1016/s0002-9149(99)00533-0

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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