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Both raloxifene and estrogen reduce major cardiovascular risk factors in healthy postmenopausal women: A 2-year, placebo-controlled study.
Author: CohenF, KenemansP, KluftC, MeijerP, MijatovicV, NetelenbosC, StehouwerC D, WattsS, de Valk-de RooG W
Original Abstract of the Article :
Currently raloxifene, a selective estrogen receptor modulator, is being investigated as a potential alternative for postmenopausal hormone replacement to prevent osteoporosis and cardiovascular disease. We compared the 2-year effects of raloxifene on a wide range of cardiovascular risk factors with ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1161/01.atv.19.12.2993
データ提供:米国国立医学図書館(NLM)
Raloxifene vs. Estrogen: Navigating the Desert of Menopause
Menopause, like a desert oasis that has dried up, marks a significant change in a woman's life, often accompanied by various challenges. This study, like a well-equipped caravan, delves into the effects of raloxifene, a selective estrogen receptor modulator, compared to conjugated equine estrogens (CEEs) on cardiovascular risk factors in postmenopausal women. The researchers, like skilled cartographers, sought to determine whether raloxifene could offer a safe and effective alternative to traditional hormone replacement therapy.Similar Destinations, Different Paths
The study's findings, like a map revealing two different routes to the same destination, show that both raloxifene and CEEs effectively reduced low-density lipoprotein cholesterol levels and fibrinogen levels, crucial factors for heart health. However, the two medications differed in their effects on other cardiovascular risk factors, with CEEs showing a greater impact on high-density lipoprotein cholesterol, triglycerides, and plasminogen activator inhibitor-1.Choosing the Right Path in the Desert of Menopause
Navigating the desert of menopause requires careful planning and understanding of the different options available. This study highlights the potential benefits and risks of both raloxifene and estrogen therapy. It emphasizes the importance of consulting with healthcare professionals to make informed decisions based on individual needs and risk factors.Dr. Camel's Conclusion
This research, like a compass guiding us through the complexities of menopause, reveals the intricate relationship between hormone therapy and cardiovascular health. It emphasizes the importance of personalized medical guidance, considering individual needs and risk factors, to navigate the desert of menopause safely and effectively.Date :
- Date Completed 1999-12-27
- Date Revised 2019-08-31
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