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Decision analysis of histamine H2-receptor antagonist maintenance therapy versus Helicobacter pylori eradication therapy: a randomised controlled trial in patients with continuing pain after duodenal ulcer.

Author: HopwoodD, MalekM, MurrayF E, PrachA T, SeniorB W, TavakoliM

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

While many studies focus on the effectiveness and cost-effectiveness of Helicobacter pylori eradication for peptic ulcers, they often emphasize eradication rates rather than symptom management and associated cost savings. Although eradication therapy is successful in clearing the infection, symptoms can persist, leading to additional costs for symptom management.
Paper Details　
Original Abstract of the Article :
Much has been published on the efficacy and cost effectiveness of Helicobacter pylori eradication treatment as an alternative to histamine H2-receptor antagonist maintenance treatment in peptic ulcer disease. However, most studies have analysed and emphasised H. pylori eradication rates rather than ...See full text at original site
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引用元：
https://doi.org/10.2165/00019053-199916040-00004

データ提供：米国国立医学図書館（NLM）

Helicobacter Pylori Eradication: A Balancing Act Between Cost and Symptom Management

The eradication of Helicobacter pylori (H. pylori) is a common treatment strategy for peptic ulcer disease. This study investigates the cost effectiveness of H. pylori eradication therapy compared to histamine H2-receptor antagonist maintenance therapy in patients experiencing persistent pain after duodenal ulcer. The study highlights the importance of considering both the cost and effectiveness of different treatment options in managing this condition.

Balancing Cost and Effectiveness: A Decision Analysis of Peptic Ulcer Treatment

The study demonstrates that while H. pylori eradication therapy is effective in clearing the infection, dyspeptic symptoms may persist. The cost of managing these persistent symptoms can be significant, leading to a need for a careful evaluation of both the cost and effectiveness of different treatment options. This study encourages a more holistic approach to managing peptic ulcer disease, considering both symptom management and cost-effectiveness.

Navigating Peptic Ulcer Disease: A Cost-Effective Approach

The study's findings suggest that a cost-effective approach to managing peptic ulcer disease may involve a combination of H. pylori eradication therapy and symptom management strategies. This can help to ensure both effective treatment of the underlying infection and relief of persistent symptoms. By carefully weighing the cost and effectiveness of different treatment options, healthcare providers can work with patients to develop personalized treatment plans that address both their health and financial needs.

Dr.Camel's Conclusion

This study highlights the complex interplay between cost and effectiveness in managing peptic ulcer disease. It encourages a nuanced approach that considers both the eradication of H. pylori and the management of persistent symptoms, ultimately aiming to optimize patient outcomes while minimizing financial burden.

Date :
  1. Date Completed 1999-12-09
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

10623364

DOI: Digital Object Identifier

10.2165/00019053-199916040-00004

Related Literature

Article Analysis
・Effective treatment of peptic ulcer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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