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Different effects of the treatment with AGN 193836 and 9-cis-retinoic acid in breast cancer cells.
Author: ChardraratnaR A, EmioniteL, IsnardiL, RaffoP, TomaS
Original Abstract of the Article :
Retinoid effects have been well studied in different cellular models, and their in vitro action on breast cancer is well known. Much less is known about the function of the different retinoid receptors in mediating retinoid activity in this and other cellular models. In order to better understand th...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/10652597
データ提供:米国国立医学図書館(NLM)
Retinoids: A New Tool in the Fight Against Breast Cancer
The search for effective treatments for breast cancer is an ongoing journey across the vast desert of medical research. This study explores the potential of retinoids, specifically focusing on AGN 193836, a synthetic compound with high affinity for the RAR alpha receptor. The authors compare the biological activities of AGN 193836 to 9cRA, a classic retinoid that binds to a wider range of retinoic acid receptors. Their findings suggest that AGN 193836, despite its selective binding, retains most of the biological activities of 9cRA, demonstrating the potential for selective retinoid agonists as a promising new avenue for breast cancer treatment. The study is like a caravan exploring different routes across the desert, seeking the most effective way to combat this disease.
Selective Retinoids: A New Oasis in the Desert of Breast Cancer Treatment
The research highlights the potential of selective retinoid agonists, such as AGN 193836, for treating breast cancer. This approach offers a more targeted and potentially less toxic treatment option, providing a new oasis in the desert of breast cancer research. The study’s findings encourage further exploration of selective retinoids as a promising strategy for combating this disease.
Navigating the Desert of Breast Cancer: A Journey of Hope
The research underscores the importance of seeking innovative and effective treatments for breast cancer. It’s like finding a new source of water in a vast and dry landscape. The study provides hope for patients battling breast cancer, offering a potential new pathway for effective treatment. The findings encourage continued research and exploration of new therapeutic approaches to combat this challenging disease.
Dr.Camel's Conclusion
This study explores the potential of selective retinoid agonists, such as AGN 193836, for treating breast cancer. It’s like discovering a new oasis in the vast desert of cancer research, offering a potential new path towards more effective and less toxic treatment options. The findings are encouraging and suggest that selective retinoids may play a significant role in the future of breast cancer treatment.
Date :
- Date Completed 2000-02-15
- Date Revised 2018-11-30
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English
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