Acute and subchronic effects of pimozide on isolation-induced aggression in male mice.

Author: ManzanequeJ M, NavarroJ F, VelascoR

Paper Details 
Original Abstract of the Article :
The aim of this study was to examine the effects of pimozide (0.25-1.25 mg/kg), administered acutely or subchronically for 10 days, on agonistic behavior elicited by isolation in male mice. Individually housed mice were exposed to anosmic "standard opponents" 90 min after pimozide injections, and th...See full text at original site
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引用元:
https://doi.org/10.1016/s0278-5846(99)00076-7

データ提供:米国国立医学図書館(NLM)

Pimozide and Its Effects on Isolation-Induced Aggression in Mice

The study of [aggression] in animal models offers valuable insights into the underlying mechanisms and potential treatments for [human aggression]. This research investigated the effects of [pimozide] on [isolation-induced aggression] in male mice, exploring the drug's potential anti-aggressive properties.

Pimozide's Anti-Aggressive Effects

The study found that [pimozide], when administered [subchronically] for 10 days, significantly reduced [offensive behaviors] such as [threat and attack] in the mice. This observation suggests that pimozide may hold potential as an [anti-aggressive] agent, offering a potential avenue for managing aggression in certain populations.

Understanding the Role of Pimozide in Aggression

Dr. Camel is fascinated by the complex interplay between [neurochemicals and behavior]. This research is like a treasure hunt in the desert of [neurobiology], unveiling the potential of pimozide to influence aggression. It's important to remember that animal studies do not always translate directly to humans, so further research is needed to fully understand pimozide's potential in treating aggressive behavior in humans.

Dr. Camel's Conclusion

This research is like a desert oasis, offering a glimpse of potential solutions to the complexities of aggression. While more research is needed, pimozide's anti-aggressive effects in animal models are promising. It's important to continue exploring the intricate relationship between neurochemicals and behavior, paving the way for a better understanding of human aggression and potential treatments.

Date :
  1. Date Completed 2000-03-02
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

10659989

DOI: Digital Object Identifier

10.1016/s0278-5846(99)00076-7

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Languages

English

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