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Evaluation of omeprazole, lansoprazole, pantoprazole, and rabeprazole in the treatment of acid-related diseases.

Author: BerardiR R, WelageL S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

PPIs are the drugs of choice in managing patients with peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. The decision to select one PPI versus another is most likely to be based on the agents' acquisition costs, formulations, FDA-labeled indications, and overall safety profiles.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To review the comparative efficacy and safety of the proton pump inhibitors (PPIs)--omeprazole, lansoprazole, pantoprazole, and rabeprazole--in the management of acid-related diseases. DATA SOURCES: English-language journal articles retrieved from a MEDLINE search from 1990 to the presen...See full text at original site
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引用元：
https://doi.org/10.1016/s1086-5802(16)31036-1

データ提供：米国国立医学図書館（NLM）

Proton Pump Inhibitors: A Comprehensive Review of Their Role in Acid-Related Diseases

The intricate workings of the human digestive system, particularly the role of stomach acid, are as complex and fascinating as the desert itself. This review delves into the realm of proton pump inhibitors (PPIs), a class of medications that effectively reduce stomach acid production. This review is like a camel caravan navigating a vast and arid landscape, seeking to understand the intricate mechanisms of acid-related diseases and their treatment. The authors of this review meticulously analyzed a vast body of literature, exploring the pharmacology, pharmacokinetics, efficacy, and safety of four widely prescribed PPIs - omeprazole, lansoprazole, pantoprazole, and rabeprazole. This thorough approach is like carefully mapping out a desert route, ensuring accuracy and comprehensiveness.

PPIs: Effective Treatment for Acid-Related Disorders

The review highlights the effectiveness of PPIs in managing a wide range of acid-related diseases, including peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. PPIs have emerged as the preferred drugs of choice, providing significant relief and improving patient outcomes. This discovery is like finding a refreshing oasis in the desert of acid-related diseases, providing a safe haven for patients seeking relief.

Understanding the Role of PPIs

This review provides a comprehensive overview of PPIs, their mechanisms of action, and their clinical applications. It emphasizes the importance of choosing the right PPI based on individual needs and considerations. This knowledge is like a valuable compass guiding patients and healthcare providers through the complexities of acid-related disorders.

Dr.Camel's Conclusion

This review provides a comprehensive overview of the role of proton pump inhibitors in managing acid-related diseases. It highlights their efficacy, safety, and the importance of selecting the right PPI for individual patient needs, offering a valuable resource for both patients and healthcare professionals.

Date :
  1. Date Completed 2000-02-24
  2. Date Revised 2019-11-03
Further Info :

Pubmed ID

10665250

DOI: Digital Object Identifier

10.1016/s1086-5802(16)31036-1

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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