Paper Details

  1. Home
  2. Paper Details

[Nasal nicotine spray in smoking cessation. Results of a multicenter study].

Author: Barrueco FerreroM, Flórez MartínS, Hernández-MezquitaM A, Jiménez RuizC A, LorzaJ J, Ramos PinedaA, Solano ReinaS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
English AbstractA summary of a research paper/publication written in English for a wider audience.

Overview

A nicotine nasal spray combined with psychological support was moderately effective in helping people quit smoking. About 35% of participants were abstinent after six months. The nasal spray caused several side effects, including nasal irritation and rhinorrhea.
Paper Details　
Original Abstract of the Article :
We have carried out an open multicenter follow-up study of the efficacy of a smoking cessation therapy that combined psychological support with use of a nicotine nasal spray. Fifty-seven subjects (37 men, 20 women) with a mean age of 40.3 +/- 15.7 yr and smoking 37.4 +/- 4.7 cigarettes per day were ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/s0300-2896(15)30005-3

データ提供：米国国立医学図書館（NLM）

Nasal Nicotine Spray: A Multi-Center Study on Smoking Cessation

We're all familiar with the allure of the desert oasis - a respite from the harshness of the surrounding environment. But what about the challenge of quitting smoking? This study, like a determined camel caravan seeking a cooler climate, explores the effectiveness of a smoking cessation therapy that combines psychological support with a nicotine nasal spray.

The study enrolled 57 subjects with a mean age of 40.3 years and an average of 37.4 cigarettes smoked daily. The participants received minimal psychological support and were prescribed the nicotine nasal spray for three months, with the dosage gradually reducing. The primary goal of the study was to assess the effectiveness of this therapy in helping people quit smoking.

A Mixed Bag of Results: Success and Challenges

The study found a success rate of 35% after six months of follow-up, with 20 out of 57 participants abstaining from smoking. While this is a decent rate, the study revealed some challenges. Most subjects used the treatment, but only a small percentage followed the appropriate doses, highlighting the importance of adherence to treatment plans.

Side Effects and Treatment Adherence

The study also found that the withdrawal syndrome was more intense during the early treatment period, a common experience for smokers trying to quit. Over three-quarters of the subjects reported side effects from the spray, the most common being nasal irritation, rhinorrhea, and tearing. Five patients discontinued the study due to intolerance to the medication.

Dr.Camel's Conclusion

This study, like a mirage in the desert, offers a glimmer of hope for those seeking to quit smoking. While the therapy showed some effectiveness, the challenges with adherence and side effects highlight the complexities of smoking cessation. The need for a more comprehensive and personalized approach to smoking cessation remains, and further research in this area is crucial.

Date :
  1. Date Completed 2000-03-10
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

10687037

DOI: Digital Object Identifier

10.1016/s0300-2896(15)30005-3

Related Literature

Article Analysis
・Side Effects of nicotine nasal spray
SNS
PICO Info
in preparation
Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.