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Nedocromil and exercise-induced asthma: acute and chronic effects.

Author: FiremanE, GreifY, KivityS, OnnA, PomeranzS, TopilskyM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Nedocromil sodium most likely reaches its maximal effect on exercise-induced asthma upon the first administration, although treatment for longer than 4 weeks might be required to prove a chronic effect of the drug.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Nedocromil sodium confers both acute and chronic protective effects in patients with bronchial asthma, the interactions of which are unknown. OBJECTIVE: To examine to what extent and for how long nedocromil sodium prevents exercise-induced asthma when given immediately before exertion c...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/10731304

データ提供：米国国立医学図書館（NLM）

Nedocromil Sodium: A Potential Solution for Exercise-Induced Asthma

This research investigates the effects of nedocromil sodium, a medication used to treat asthma, in preventing exercise-induced asthma. The study involved 18 asthmatic patients who received nedocromil sodium either acutely before exertion or after chronic administration. The results demonstrate that nedocromil sodium effectively reduces exercise-induced asthma symptoms, both when given acutely and after chronic treatment. However, the researchers found no significant difference in effectiveness between acute and chronic administration, suggesting that the drug reaches its maximum effect upon the initial dose.

Managing Asthma Symptoms: Finding the Right Approach

The study provides valuable insights into the use of nedocromil sodium in managing exercise-induced asthma, indicating its efficacy in reducing symptoms both acutely and with chronic administration. However, the research suggests that the maximum effect of the drug is achieved upon the first dose, with no further improvement observed with prolonged treatment. This finding highlights the importance of individualized treatment plans and careful monitoring to determine the optimal dosage and timing of nedocromil sodium for managing asthma symptoms.

Navigating Asthma: A Personalized Journey

The study reinforces the need for a personalized approach to managing asthma. While nedocromil sodium shows promise in reducing exercise-induced asthma symptoms, individual responses to medications can vary significantly. Regular communication with your physician and a comprehensive understanding of your condition are crucial for achieving optimal asthma management.

Dr.Camel's Conclusion

Imagine the desert landscape where the air can be harsh and unpredictable, just like the challenges of asthma. This research, like a seasoned desert guide, provides valuable information about the effectiveness of nedocromil sodium in managing exercise-induced asthma, helping individuals navigate this challenging terrain with greater confidence and control.
Date :
  1. Date Completed 2000-04-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10731304

DOI: Digital Object Identifier

10731304

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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