Experience with quinupristin/dalfopristin in treating infections with vancomycin-resistant Enterococcus faecium in children.

Author: BeathS V, DarbyshireP J, GrayJ W, KellyD, MannJ R

Paper Details 
Original Abstract of the Article :
The emergence and spread of vancomycin-resistant Enterococcus faecium (VREF) has presented serious therapeutic difficulties because of the lack of reliably active antibiotics. Quinupristin/dalfopristin is a new injectable streptogramin antibiotic that is active against most strains of VREF. Experien...See full text at original site
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引用元:
https://doi.org/10.1097/00006454-200003000-00012

データ提供:米国国立医学図書館(NLM)

Quinpristin/Dalfopristin: A Beacon of Hope for VREF Infections in Children

Vancomycin-resistant Enterococcus faecium (VREF) is a formidable foe in the world of infectious diseases. This bacteria, like a desert sandstorm, can wreak havoc on the body's defenses. This research explores the use of quinupristin/dalfopristin, a new streptogramin antibiotic, in treating VREF infections in children. The study reports on a compassionate use protocol involving eight children with VREF infections who received quinupristin/dalfopristin.

A New Antibiotic: A Potential Oasis for VREF Infections

The findings suggest that quinupristin/dalfopristin, like a shimmering oasis in the desert, can provide a valuable treatment option for VREF infections in children. The antibiotic demonstrated activity against most strains of VREF, offering hope for overcoming this challenging infection. The study highlights the importance of exploring new antibiotic treatments to combat the growing threat of antibiotic resistance.

Combating Antibiotic Resistance

This research underscores the urgent need to develop new antibiotics to combat the growing problem of antibiotic resistance. VREF is a prime example of the challenges posed by antibiotic resistance, and the need for innovative treatments to address these challenges is paramount. It's a call to action, reminding us to be vigilant in our fight against this silent threat.

Dr.Camel's Conclusion

This study offers a glimmer of hope in the fight against antibiotic resistance. Quinpristin/dalfopristin provides a potential treatment option for VREF infections in children, but more research is needed to fully understand its efficacy and safety profile in this vulnerable population.

Date :
  1. Date Completed 2000-05-10
  2. Date Revised 2019-08-18
Further Info :

Pubmed ID

10749466

DOI: Digital Object Identifier

10.1097/00006454-200003000-00012

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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