Alendronate in early postmenopausal women: effects on bone mass during long-term treatment and after withdrawal. Alendronate Osteoporosis Prevention Study Group.

Author: DaifotisA, FogelmanI, FuleihanG E, GilchristN L, KrupaD, McClungM R, RavnP, Rodriguez-PortalesJ A, SambrookP, WasnichR D, WeissS R, YatesA J

Paper Details 
Original Abstract of the Article :
We studied the effect on bone mass of alendronate treatment for 5 yr and its withdrawal. Four hundred and forty-seven postmenopausal women with normal bone mass entered a 3-yr randomized trial followed by a 2-yr open label extension. Three hundred and eleven women completed the first 3 yr, and 263 c...See full text at original site
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引用元:
https://doi.org/10.1210/jcem.85.4.6549

データ提供:米国国立医学図書館(NLM)

Building Strong Bones with Alendronate

Bone health is a vital aspect of overall well-being, like the foundation of a sturdy desert fortress. This study investigates the long-term effects of alendronate, a medication used to prevent osteoporosis, in postmenopausal women. The researchers analyzed data from a large clinical trial to determine the impact of alendronate on bone mineral density (BMD) over time.

A Strong Foundation for the Future

The study found that alendronate significantly increased BMD at the spine and trochanter, suggesting that it effectively prevents bone loss in postmenopausal women. The medication also stabilized BMD at other sites, such as the total body and femoral neck. These findings highlight the potential of alendronate to protect against osteoporosis and reduce the risk of fractures. It's like building a sturdy wall around the desert fortress, protecting it from the harsh elements.

A Healthy Journey Through Life

The study emphasizes the importance of bone health, especially for postmenopausal women who are at increased risk for osteoporosis. Alendronate has emerged as a valuable tool for preventing bone loss and promoting bone health. It's like having a reliable camel to carry us through the desert, ensuring a safe and comfortable journey.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of alendronate in preventing bone loss. It's like discovering a new type of oasis in the desert, offering a safe haven for bone health and ensuring a strong foundation for the future.

Date :
  1. Date Completed 2000-05-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10770187

DOI: Digital Object Identifier

10.1210/jcem.85.4.6549

Related Literature

SNS
PICO Info
in preparation
Languages

English

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