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Chlorpromazine versus placebo for schizophrenia.

Author: AdamsC E, AwadG, ThornleyB

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Chlorpromazine is a well-established treatment for schizophrenia, but it is associated with many adverse effects, including sedation, movement disorders, and weight gain.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Chlorpromazine, formulated in the 1950s, remains a benchmark treatment for those with schizophrenia. OBJECTIVES: To evaluate the effects of chlorpromazine for schizophrenia in comparison to placebo. SEARCH STRATEGY: Electronic searches of Biological Abstracts (1982-1995), The Cochrane ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/14651858.CD000284

データ提供：米国国立医学図書館（NLM）

Chlorpromazine for Schizophrenia: A Well-Established Treatment

Schizophrenia is a complex and challenging mental health condition, often likened to a desert of distorted perceptions and altered reality. This research examines the effectiveness of chlorpromazine, a well-established antipsychotic medication, in treating schizophrenia, comparing its effects to a placebo. The study explores the benefits and risks associated with chlorpromazine, providing valuable insights into its role in managing this complex condition.

Navigating the Desert of Schizophrenia

The study found that chlorpromazine is effective in reducing relapse and promoting global improvement in symptoms and functioning for individuals with schizophrenia. It's like finding a reliable guide in a vast and confusing desert, helping people navigate the challenges of schizophrenia and find a path to stability. However, the study also highlights the significant side effects associated with chlorpromazine, including sedation, movement disorders, and weight gain.

A Balancing Act: Weighing the Benefits and Risks

This research is a reminder that the desert of schizophrenia requires a careful balance between the benefits and risks of different treatment options. It's like choosing the right path in a desert, considering the terrain, the weather, and the resources available. By understanding the effectiveness and side effects of chlorpromazine, clinicians can make informed decisions to optimize treatment and improve the quality of life for individuals with schizophrenia.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness and limitations of chlorpromazine in treating schizophrenia. It's a reminder that the desert of schizophrenia requires a careful balance between the benefits and risks of different treatment options. While chlorpromazine has proven effective in managing this complex condition, understanding its side effects is crucial for making informed treatment decisions.

Date :
  1. Date Completed 2000-07-06
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

10796338

DOI: Digital Object Identifier

10.1002/14651858.CD000284

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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