Paper Details

  1. Home
  2. Paper Details

Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.

Author: LethabyA, SowterM, VollenhovenB

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Uterine fibroids are common, affecting 25-35% of women over 35. While some fibroids don’t cause symptoms, up to 50% cause severe problems requiring treatment. Surgery is the standard treatment for fibroids, which are stimulated to grow by estrogen. Gonadotropin-releasing hormone agonists (GnRHa) can shrink fibroids by reducing estrogen levels, but cannot be used long-term due to side effects. GnRHa can be used before surgery to shrink the fibroids and reduce bleeding.
Paper Details　
Original Abstract of the Article :
Uterine fibroids, smooth muscle tumours of the uterus, are found in at least 25 to 35% of women over the age of 35 years. Although some of these tumours are asymptomatic, up to 50% cause symptoms severe enough to warrant therapy and surgery is the standard treatment. Fibroid growth is stimulated by ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/14651858.CD000547

データ提供：米国国立医学図書館（NLM）

Pre-operative GnRH Analogue Therapy for Uterine Fibroids: A Potential Treatment Approach

This research explores a potential treatment strategy for uterine fibroids, a common condition affecting women. This study investigates the use of gonadotropin-releasing hormone agonists (GnRHa) as pre-operative therapy for uterine fibroids. The researchers examined the potential benefits of GnRHa treatment in reducing fibroid size and uterine volume before surgery. The study aims to [主な目的] and explore the feasibility of GnRHa as a pre-operative adjunct to surgery for uterine fibroids. This research provides insights into the potential role of GnRHa in managing uterine fibroids before surgery.

GnRH Analogues: A Potential Pre-operative Treatment Option for Uterine Fibroids

The study demonstrates the potential benefits of GnRHa treatment in reducing fibroid size and uterine volume before surgery. [研究結果] These findings suggest that GnRHa could be a valuable pre-operative tool for managing uterine fibroids, potentially leading to improved surgical outcomes.

Health Implications and Lifestyle Considerations

This research highlights the importance of personalized approaches to treating uterine fibroids. [健康的なベネフィットもしくはリスク] It is crucial to discuss treatment options with healthcare professionals to determine the best course of action based on individual needs and preferences.

Dr.Camel's Conclusion

This research offers a valuable contribution to the understanding of GnRHa therapy in managing uterine fibroids. It emphasizes the importance of exploring pre-operative options to improve surgical outcomes and enhance the overall well-being of patients. The study encourages continued research to optimize the use of GnRHa therapy and provide women with effective treatment options for uterine fibroids.

Date :
  1. Date Completed 2000-07-06
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

10796723

DOI: Digital Object Identifier

10.1002/14651858.CD000547

Related Literature

Article Analysis
・Effective treatment of uterine fibroids
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.