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Early results of LH-RH agonist treatment with or without chlormadinone acetate for hormone therapy of naive localized or locally advanced prostate cancer: a prospective and randomized study. The Prostate Cancer Study Group.

Author: AkazaH, AsoY, HiraoY, HommaY, MoriyamaN, OhashiY, OkadaK, TsushimaT, UsamiM, YokoyamaM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While surgery is often the preferred treatment for localized and some advanced prostate cancer, it's not always suitable for every patient. This study examines the effectiveness of primary hormone therapy as an alternative treatment for these patients in a prospective, randomized trial.
Paper Details　
Original Abstract of the Article :
The majority of patients with localized and some cases of locally advanced prostate cancer undergo radical prostatectomy. However, radical prostatectomy cannot always be selected for those patients. In this situation, primary hormone therapy is an alternative treatment option. We have designed a pro...See full text at original site
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引用元：
https://doi.org/10.1093/jjco/hyd035

データ提供：米国国立医学図書館（NLM）

A New Frontier in Prostate Cancer Treatment: LH-RH Agonist Therapy

Prostate cancer, a common malignancy affecting men, often requires treatment to prevent its progression. This study explores the efficacy of LH-RH agonist therapy, a hormonal treatment that suppresses testosterone production, in managing prostate cancer. The researchers conducted a prospective randomized trial comparing LH-RH agonist therapy alone to LH-RH agonist therapy combined with chlormadinone acetate, another hormone-modulating agent, in 120 men with localized or locally advanced prostate cancer. The study aims to evaluate the effectiveness of these treatments in controlling the disease and provide insights into potential benefits and risks.

Navigating the Desert of Prostate Cancer

Prostate cancer is a challenging foe, requiring a strategic approach for effective management. This study explores the potential of LH-RH agonist therapy, a weapon in the arsenal of prostate cancer treatment. The researchers aim to uncover the optimal approach for utilizing LH-RH agonists, seeking to strike a balance between controlling the disease and minimizing side effects. It’s like navigating a desert landscape – choosing the right path to navigate through the challenges and ensure a successful journey.

A Personalized Approach to Treatment

This research highlights the importance of individualized treatment strategies for prostate cancer. The study’s findings could inform the development of more targeted and effective treatment plans, helping to optimize outcomes for men with this disease.

Dr.Camel's Conclusion

This study delves into the potential of LH-RH agonist therapy for managing prostate cancer. It's like finding a hidden oasis in the vast desert of prostate cancer research – a source of hope and new possibilities for treatment. While further research is needed, the findings provide valuable insights into the potential benefits and risks of this approach.

Date :
  1. Date Completed 2000-05-22
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

10798540

DOI: Digital Object Identifier

10.1093/jjco/hyd035

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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