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Mycophenolate mofetil versus azathioprine in patients with chronic active ulcerative colitis: a 12-month pilot study.

Author: GalleP R, KrummenauerF, MayetW J, NeurathM F, OrthT, PetersM, SchlaakJ F, WanitschkeR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effectiveness and safety of mycophenolate mofetil (MMF) with prednisolone to azathioprine (AZA) with prednisolone for treating chronic active ulcerative colitis (UC). Both AZA and MMF are immunosuppressants used for UC, but there are limited alternative treatments available. The study aimed to determine which combination was more beneficial for patients with UC.
Paper Details　
Original Abstract of the Article :
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) of unknown etiology frequently requiring long-term therapy for control of symptoms and prevention of relapse. Azathioprine (AZA) has been shown to be effective and safe in the treatment of chronic active UC. However, the alternatives to ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1572-0241.2000.02010.x

データ提供：米国国立医学図書館（NLM）

Mycophenolate Mofetil vs. Azathioprine: A Battle in the Desert of Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, a persistent storm in the desert of the digestive system. This study compared the effectiveness and safety of two immunosuppressive medications, mycophenolate mofetil (MMF) and azathioprine (AZA), in treating patients with chronic active UC. The researchers conducted a 12-month pilot study to evaluate the relative efficacy and safety of these medications.

The study found that MMF/prednisolone was comparable to AZA/prednisolone in terms of efficacy and safety, suggesting that MMF could be a viable alternative for patients with chronic active UC. It's like finding a new oasis in the desert, offering a different route to relief and healing.

A New Oasis in the Desert of UC Treatment

The study suggests that MMF may offer a valuable alternative treatment option for patients with chronic active UC. It's like discovering a hidden spring in the desert, providing a new source of hope and relief for those battling this challenging disease.

Finding a More Comfortable Oasis

The study provides hope for individuals with UC, indicating that MMF may offer a comparable treatment option with potentially fewer side effects. It's like finding a more comfortable oasis in the desert, one that offers not only water and shade, but also a sense of comfort and well-being.

Dr.Camel's Conclusion

This study opens the door to new possibilities for UC treatment, suggesting that MMF may be a valuable addition to the existing arsenal of therapies. It's a reminder that even in the vast and often unforgiving landscape of disease, there's always the potential for new discoveries and advancements.

Date :
  1. Date Completed 2000-05-30
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

10811328

DOI: Digital Object Identifier

10.1111/j.1572-0241.2000.02010.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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