A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators.

Author: FeaganB G, FedorakR N, GreenbergG R, HanauerS B, HopkinsM, IrvineE J, KovalJ, McDonaldJ W, SteinhartA H, SutherlandL, WildG, WongC J

Paper Details 
Original Abstract of the Article :
BACKGROUND: Patients with Crohn's disease often have relapses. Better treatments are needed for the maintenance of remission. Although methotrexate is an effective short-term treatment for Crohn's disease, its role in maintaining remissions is not known. METHODS: We conducted a double-blind, placeb...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM200006013422202

データ提供:米国国立医学図書館(NLM)

Methotrexate for Maintaining Remission in Crohn's Disease

In the vast desert of gastroenterology, we're constantly seeking new ways to manage the debilitating symptoms of Crohn's disease. This study, like a meticulous investigation of the intricate sand dunes of Crohn's, explores the effectiveness of methotrexate in maintaining remission. The researchers, like skilled engineers building bridges across a seemingly insurmountable gap, are investigating the potential of methotrexate to help patients achieve and maintain long-term remission.

Their findings, like a promising oasis in the desert, reveal that methotrexate is effective in maintaining remission in patients with Crohn's disease who have achieved remission after initial treatment. The study found that patients receiving methotrexate were significantly less likely to relapse and required less prednisone compared to those receiving placebo. This research, like a beacon of hope, illuminates a path towards a brighter future for patients with Crohn's.

A New Hope for Crohn's Patients

This study, like a groundbreaking discovery in the desert, provides a new hope for patients with Crohn's disease. The findings suggest that methotrexate can play a significant role in managing this challenging condition and improving patients' quality of life. This research underscores the importance of exploring new and innovative therapies to meet the needs of those living with Crohn's.

Navigating the Desert of Crohn's

For those navigating the challenging landscape of Crohn's disease, this study offers a glimmer of hope. The findings suggest that methotrexate may be a valuable tool in managing this condition and achieving long-term remission. This research underscores the importance of working closely with a gastroenterologist to develop a personalized treatment plan that addresses individual needs and goals. By staying informed and actively engaging in their care, patients with Crohn's can effectively manage their symptoms and improve their quality of life.

Dr.Camel's Conclusion

This research provides valuable insights into the role of methotrexate in maintaining remission in Crohn's disease. The findings suggest that methotrexate can be a valuable tool in managing this challenging condition and improving patients' quality of life. This study underscores the importance of exploring new and innovative therapies to meet the needs of those living with Crohn's.

Date :
  1. Date Completed 2000-06-01
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

10833208

DOI: Digital Object Identifier

10.1056/NEJM200006013422202

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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