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Loratadine versus cetirizine: assessment of somnolence and motivation during the workday.

Author: GatesD, GreidingL, HeithoffK, RamonF, SalmunL M, ScharfM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cetirizine promotes somnolence and decreases motivation to perform activities during the workday compared with loratadine in patients with allergic rhinitis.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: This parallel-group, double-blind study compared the somnolence and motivation profiles of 2 second-generation antihistamines, loratadine and cetirizine, in patients with allergic rhinitis. BACKGROUND: Second-generation antihistamines were developed to provide symptomatic relief from all...See full text at original site
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引用元：
https://doi.org/10.1016/S0149-2918(00)80045-4

データ提供：米国国立医学図書館（NLM）

The Effects of Second-Generation Antihistamines on Workday Performance

For individuals with [allergic rhinitis], finding an antihistamine that provides relief without compromising workday productivity is a top priority. This study compared the effects of [loratadine and cetirizine], two second-generation antihistamines, on [somnolence and motivation]. The researchers conducted a [double-blind study] with [patients aged 12 years and older] and found that [cetirizine] was associated with increased somnolence and reduced motivation compared to [loratadine].

Choosing the Right Antihistamine

The study's findings highlight a key difference between two commonly used second-generation antihistamines. While both medications effectively alleviate [allergic rhinitis symptoms], [cetirizine] appears to have a greater impact on [cognitive function]. This information can help individuals with [allergic rhinitis] and their healthcare providers choose the most appropriate antihistamine based on individual needs and priorities.

Staying Alert and Focused

Just as a camel navigates the desert, we all need to stay alert and focused to navigate our daily lives. This study reminds us that even medications intended to relieve symptoms can have varying effects on cognitive function. Choosing the right antihistamine can make a difference in workday productivity and overall well-being. It's important to discuss these considerations with a healthcare professional and make informed decisions about medications.

Dr.Camel's Conclusion

Choosing the right antihistamine is like selecting the right camel for a long desert journey. Loratadine, like a sturdy and reliable camel, may be the better choice for those who need to stay alert and focused throughout the day. Cetirizine, on the other hand, might be more suitable for those who are less concerned about daytime drowsiness. Ultimately, finding the best antihistamine for your needs requires careful consideration and a conversation with your healthcare provider.

Date :
  1. Date Completed 2000-10-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10868555

DOI: Digital Object Identifier

10.1016/S0149-2918(00)80045-4

Related Literature

Article Analysis
・Side Effects of loratadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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