Pharmacologic treatment of the irritable bowel syndrome: a systematic review of randomized, controlled trials.

Author: ImperialeT F, JailwalaJ, KroenkeK

Paper Details 
Original Abstract of the Article :
PURPOSE: To evaluate the efficacy of pharmacologic agents for the irritable bowel syndrome. DATA SOURCES: Electronic literature search of MEDLINE (1966 to 1999), EMBASE (1980 to 1999), PsycINFO (1967 to 1999), and the Cochrane controlled trials registry and a manual search of references from biblio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.7326/0003-4819-133-2-200007180-00013

データ提供:米国国立医学図書館(NLM)

Irritable Bowel Syndrome: A Search for Effective Treatments

The study of [irritable bowel syndrome (IBS)] is an ongoing challenge, with researchers seeking to understand and effectively manage this common gastrointestinal disorder. This research delves into the effectiveness of various pharmacologic agents for treating IBS.

The authors conducted a systematic review of randomized controlled trials, evaluating the efficacy of different medication classes for IBS. Their findings reveal that smooth-muscle relaxants show the strongest evidence for efficacy, particularly in patients with abdominal pain as the predominant symptom. Loperamide was found to be effective in reducing diarrhea but not in relieving abdominal pain.

Finding Relief from IBS Symptoms

The study's findings provide valuable insights for clinicians seeking to manage IBS symptoms. The authors' analysis highlights the importance of considering individual patient needs and choosing medications that target the specific symptoms they are experiencing.

Navigating the Options

This research underscores the importance of a comprehensive approach to IBS management. While pharmacologic agents can provide relief from certain symptoms, lifestyle modifications, such as dietary changes and stress management techniques, are also crucial for long-term well-being.

Dr.Camel's Conclusion

Navigating the complexities of IBS is like traversing a desert landscape filled with unexpected challenges. This research offers a roadmap for clinicians, providing insights into the effectiveness of different treatment options. Like a wise camel, we should approach IBS management with a multifaceted strategy, considering both medication and lifestyle modifications to ensure optimal outcomes for patients.

Date :
  1. Date Completed 2000-07-13
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

10896640

DOI: Digital Object Identifier

10.7326/0003-4819-133-2-200007180-00013

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.