Troglitazone or metformin in combination with sulfonylureas for patients with type 2 diabetes?

Author: KirkJ K, MichielutteR, PearceK A, SummersonJ H

Paper Details 
Original Abstract of the Article :
BACKGROUND: Combination oral therapy is often used to control the hyperglycemia of patients with type 2 diabetes. We compared the effectiveness of metformin and troglitazone when added to sulfonylurea therapy for patients with type 2 diabetes who had suboptimal blood glucose control. METHODS: We us...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10907625

データ提供:米国国立医学図書館(NLM)

Comparing the Effectiveness of Metformin and Troglitazone

Type 2 diabetes is a tricky camel to ride, often requiring a combination of therapies to manage blood sugar levels. This study delves into the effectiveness of two popular medications, metformin and troglitazone, when added to existing sulfonylurea therapy. The researchers conducted a randomized trial to compare the efficacy, safety, and tolerability of these drugs in patients with type 2 diabetes who were not achieving optimal blood sugar control with diet and sulfonylureas alone. Their findings shed light on the effectiveness of these medications in treating type 2 diabetes.

Both Metformin and Troglitazone Show Promise

The study found that both metformin and troglitazone significantly improved blood sugar control in patients with type 2 diabetes who were not achieving optimal control with diet and sulfonylureas alone. Both medications were also well-tolerated and did not show any significant differences in terms of side effects.

A Smoother Ride for Diabetes

The study's findings provide valuable information for physicians and patients with type 2 diabetes. Both metformin and troglitazone offer effective treatment options, potentially leading to better blood sugar control and improved overall health. It's like finding a sturdy camel saddle that makes the journey through the desert of diabetes a little smoother!

Dr.Camel's Conclusion

This study underscores the effectiveness of both metformin and troglitazone in improving blood sugar control in patients with type 2 diabetes who are not achieving optimal control with diet and sulfonylureas alone. The study's findings provide valuable information for physicians and patients seeking effective treatment options for this chronic condition. These medications offer a promising pathway to better blood sugar control and improved overall health for individuals with type 2 diabetes.

Date :
  1. Date Completed 2000-08-10
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

10907625

DOI: Digital Object Identifier

10907625

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PICO Info
in preparation
Languages

English

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