Progression of radiographic joint erosion during low dose corticosteroid treatment of rheumatoid arthritis.

Author: Di PrimeoD, GenantH K, LynchJ M, PaulusH E, SandaM, SchwartzB A, SharpJ T, WeissmanB N

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The reported prevention of joint damage during treatment with prednisolone 7.5 mg daily in patients with early rheumatoid arthritis (RA)3 may have important implications for management of RA. We evaluated this observation in another patient population. METHODS: Radiographic progression r...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10914843

データ提供:米国国立医学図書館(NLM)

Low-Dose Corticosteroids and Radiographic Joint Erosion in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints, causing pain, inflammation, and damage. This research investigates the effect of low-dose corticosteroids on the progression of joint damage in patients with RA. The researchers analyzed radiographic data from a large group of patients with RA who participated in a clinical trial comparing the effectiveness of different nonsteroidal anti-inflammatory drugs (NSAIDs). They found that low-dose corticosteroids did not prevent the progression of joint erosion, suggesting that these medications may not be effective at slowing down joint damage in RA.

Low-Dose Corticosteroids: Not a Cure-All

While corticosteroids can be effective at reducing inflammation and pain in RA, this study suggests that they may not be sufficient to prevent the long-term progression of joint damage. This is a significant finding, as corticosteroids are often used in RA treatment. The researchers recommend further investigation into the role of corticosteroids in RA management, particularly in relation to joint damage.

Understanding the Landscape of RA: A Complex Journey

RA is a complex and challenging disease, and finding the right treatment strategy can be like navigating a vast and unforgiving desert. This research sheds light on the limitations of low-dose corticosteroids in preventing joint damage, emphasizing the need for a multi-faceted approach to RA treatment. Patients and healthcare providers should work together to develop a tailored treatment plan that addresses the specific needs of each individual.

Dr.Camel's Conclusion

The quest for effective RA treatments continues. This research adds valuable insights to our understanding of this complex disease, emphasizing the need for a comprehensive approach that includes both medications and lifestyle interventions. Remember, RA is a marathon, not a sprint, and a collaborative effort between patients and healthcare providers is essential to navigating this challenging journey.

Date :
  1. Date Completed 2000-11-16
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

10914843

DOI: Digital Object Identifier

10914843

Related Literature

SNS
PICO Info
in preparation
Languages

English

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