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A palliative accelerated irradiation regimen for advanced non-small-cell lung cancer vs. conventionally fractionated 60 GY: results of a randomized equivalence study.

Author: AbelU, NestleU, NiederC, SchnabelK, SybrechtG W, UkenaD, WalterK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared palliative treatment to more intensive treatment in patients with advanced non-small-cell lung cancer (NSCLC) who are not candidates for radical treatment.
Paper Details　
Original Abstract of the Article :
Radiation oncologists are often faced with patients with advanced non-small-cell lung cancer (NSCLC), who are not suitable candidates for state-of-the-art radical treatment, but who also are not judged to have a very short life expectancy. Some physicians treat these patients palliatively, whereas o...See full text at original site
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引用元：
https://doi.org/10.1016/s0360-3016(00)00607-6

データ提供：米国国立医学図書館（NLM）

Palliative Accelerated Irradiation for Advanced Non-Small-Cell Lung Cancer: A Desert of Treatment Options

This study explores the complex landscape of treatment options for advanced non-small-cell lung cancer (NSCLC), a challenging disease that requires careful consideration of patient needs and prognosis. The researchers aimed to determine whether a palliative accelerated irradiation regimen was comparable in effectiveness to a conventional fractionated regimen. The study found that the accelerated regimen was as effective as the conventional regimen, suggesting it could be a valuable alternative for patients with a limited life expectancy. This research is like finding a new pathway through a vast and unpredictable desert, offering a potentially more efficient and effective treatment approach for patients with advanced NSCLC.

Accelerated Irradiation: A Time-Efficient Approach

The researchers found that a palliative accelerated irradiation regimen was as effective as a conventional fractionated regimen in treating advanced NSCLC. This is like finding a shortcut across the desert, enabling faster and more efficient delivery of treatment to patients with a limited life expectancy. The study's findings suggest that accelerated irradiation could be a viable alternative for patients who need palliative care and may not be able to tolerate a lengthy treatment course.

Navigating Lung Cancer Treatment: A Desert of Complexity

Lung cancer is a challenging disease, and treatment options vary depending on the stage, patient characteristics, and prognosis. This study provides valuable insights into the potential effectiveness of accelerated irradiation as a palliative treatment option for patients with advanced NSCLC. The researchers' findings highlight the importance of individualizing treatment plans based on each patient's specific needs and goals.

Dr. Camel's Conclusion

This study provides valuable insights into the effectiveness of accelerated irradiation as a palliative treatment option for patients with advanced non-small-cell lung cancer. The researchers' findings suggest that accelerated irradiation could be a viable alternative for patients who require palliative care, offering a potentially more time-efficient and effective approach to treatment.
Date :
  1. Date Completed 2000-08-17
  2. Date Revised 2019-07-08
Further Info :

Pubmed ID

10924977

DOI: Digital Object Identifier

10.1016/s0360-3016(00)00607-6

Related Literature

Article Analysis
・Effective treatment of lung cancer
SNS
PICO Info
in preparation
Languages

English

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