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Associated or combined vaccination of Brazilian infants with a conjugate Haemophilus influenzae type b (Hib) vaccine, a diphtheria-tetanus-whole-cell pertussis vaccine and IPV or OPV elicits protective levels of antibodies against Hib.

Author: AraújoO O, CarvalhoE S, FarhatC K, Forleo-NetoE, PucciniR F, VespaG N, WeckxL W

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the immunogenicity and safety of including a Haemophilus influenzae type b vaccine (PRP-T) in three different vaccination schemes. All three schemes resulted in satisfactory antibody production against PRP, diphtheria, tetanus, and pertussis antigens.
Paper Details　
Original Abstract of the Article :
This study investigated the immunogenicity and safety of including a Haemophilus influenzae type b vaccine (polyribosylribitol phosphate conjugated to tetanus toxoid, PRP-T) in three different vaccination schemes: (1) PRP-T reconstituted with a combined diphtheria-tetanus-pertussis-inactivated polio...See full text at original site
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引用元：
https://doi.org/10.1016/s0264-410x(00)00093-1

データ提供：米国国立医学図書館（NLM）

The Effectiveness of Combined Vaccination for Haemophilus influenzae Type b

In the world of [immunology], we strive to protect ourselves and our children from infectious diseases. One of the major triumphs of modern medicine is the development of vaccines, which help our immune systems build defenses against harmful pathogens. Haemophilus influenzae type b (Hib), a bacteria that can cause serious infections in children, is a particular concern, and vaccines have been instrumental in reducing its incidence. This study explores different vaccination strategies for Hib.

The researchers examined three different vaccination schedules, comparing the effectiveness of Hib conjugate vaccine (PRP-T) combined with other vaccines, such as diphtheria-tetanus-pertussis (DTP) and polio vaccines. This is like creating a desert oasis, a haven of immunity for children against multiple diseases.

Successful Immunization Strategy

The study found that all three vaccination schedules were effective in inducing protective levels of antibodies against Hib. This was a resounding success, showing that the Hib conjugate vaccine can be safely and effectively incorporated into routine immunization programs. It's like finding a hidden spring in the desert, a source of protection for children.

A Healthier Future for Children

This research suggests that we can effectively protect children from Hib infection by incorporating the Hib conjugate vaccine into routine immunization programs. This means fewer children will suffer from the serious consequences of Hib disease. It's like planting a seed in the desert, a seed of hope for a healthier future for our children.

Dr.Camel's Conclusion

This research showcases the importance of combined vaccinations in protecting children. It's like finding a caravan route that leads to a safer and healthier future for our children.

Date :
  1. Date Completed 2000-10-12
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

10930692

DOI: Digital Object Identifier

10.1016/s0264-410x(00)00093-1

SNS
PICO Info
in preparation
Languages

English

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