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Bone density changes during two years treatment with tibolone or conjugated estrogens and norgestrel, compared with untreated controls in postmenopausal women.

Author: GilliganE, HarrisonR F, KellyA, MilnerM

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Both tibolone and conjugated estrogens plus sequential norgestrel were effective in preventing osteoporosis, as shown by significant increases in bone mineral density (BMD) compared to a no-treatment control group. Without treatment, BMD declined postmenopausally.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To quantify and compare the effect of two different hormone replacement therapy regimens on bone mineral density (BMD) and serum alkaline phosphate levels against a group of no treatment control volunteers. METHODS: An open 104-week comparative study of 113 early postmenopausal women. Fi...See full text at original site
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引用元：
https://doi.org/10.1097/00042192-200007050-00007

データ提供：米国国立医学図書館（NLM）

Tibolone and Conjugated Estrogens: A Battle Against Bone Loss

As we navigate the sands of time, our bodies undergo changes, and bone density can decline, especially after menopause. This study investigates the effects of two different hormone replacement therapies (HRTs), tibolone and conjugated estrogens, on bone mineral density (BMD) in postmenopausal women.

HRT: A Lifeline Against Bone Loss

The study found that both tibolone and conjugated estrogens significantly increased BMD compared to untreated controls. Imagine a camel encountering a sandstorm but finding shelter in a sturdy oasis—HRT can provide a similar protective effect against bone loss. The findings suggest that HRT can play a crucial role in preventing osteoporosis.

Protecting Bone Health: A Desert Oasis

This research offers valuable insights into bone health during menopause. It highlights the potential of HRT in mitigating bone loss and promoting overall well-being. Just as a camel thrives in a desert oasis, we can seek solutions that nourish our bodies and protect our health.

Dr. Camel's Conclusion

This study demonstrates the effectiveness of hormone replacement therapies in combating bone loss during menopause. It highlights the importance of understanding the changing needs of our bodies as we navigate the sands of time. Just as a camel adapts its strategies to survive in the desert, we can utilize medical advancements to protect our health and well-being.
Date :
  1. Date Completed 2001-03-08
  2. Date Revised 2019-11-04
Further Info :

Pubmed ID

10993032

DOI: Digital Object Identifier

10.1097/00042192-200007050-00007

Related Literature

Article Analysis
・Effective treatment of bone density
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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