Additive effects of combined treatment with etidronate and alfacalcidol on bone mass and mechanical properties in ovariectomized rats.

Author: KatsumataT, KawaguchiH, KogitaK, ManabeN, NakamuraK, NishikawaT, OgawaS

Paper Details 
Original Abstract of the Article :
The present study was undertaken to evaluate the effects of combined treatment with intermittent cyclical etidronate and daily alfacalcidol on the mass and the mechanical properties of bone in ovariectomized rats, and to compare the effects with those of single treatments. Seventy 14-week-old female...See full text at original site
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引用元:
https://doi.org/10.1016/s8756-3282(00)00386-0

データ提供:米国国立医学図書館(NLM)

Combined Treatment for Bone Loss in Ovariectomized Rats

This study explores the effects of combined treatment with etidronate and alfacalcidol on bone mass and mechanical properties in ovariectomized rats. The researchers wanted to see if combining these two drugs could be more effective than using them individually in preventing bone loss, a common problem after menopause. It's like examining the resilience of a desert oasis, seeking ways to strengthen its structure and preserve its beauty against the harsh elements.

A Stronger Foundation for Bones

The researchers discovered that the combined treatment of etidronate and alfacalcidol significantly increased bone mineral density and improved mechanical properties in ovariectomized rats. These results suggest that the combined treatment could be more effective than single treatments in preventing bone loss and maintaining bone health. It's like fortifying the foundations of a desert oasis with strong materials, making it more resistant to the challenges of its environment. This study provides valuable insights into the potential of combined treatment strategies for bone loss.

Maintaining Bone Health

This research highlights the importance of maintaining bone health throughout life, particularly after menopause. The findings suggest that combined treatment with etidronate and alfacalcidol could play a crucial role in preventing bone loss and fractures, leading to a better quality of life. Imagine, having strong, resilient bones, like the sturdy legs of a camel that can traverse the vast desert landscape with ease!

Dr. Camel's Conclusion

This study emphasizes the potential benefits of combining etidronate and alfacalcidol to combat bone loss in women after menopause. It's a testament to the power of collaborative efforts in finding solutions to complex health challenges. It's a reminder that we must constantly strive to improve our understanding of bone health and develop effective treatments to maintain its strength and resilience, just as a camel must continually replenish its reserves to endure the harsh desert environment.

Date :
  1. Date Completed 2000-12-04
  2. Date Revised 2019-09-06
Further Info :

Pubmed ID

11062351

DOI: Digital Object Identifier

10.1016/s8756-3282(00)00386-0

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English

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