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A controlled trial of the early treatment of secondary hyperparathyroidism with calcitriol in hemodialysis patients.

Author: DelmezJ A, GilesK S, KelberJ, NorwoodK Y, SlatopolskyE

Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study discusses the use of calcitriol in treating secondary hyperparathyroidism in dialysis patients and its limitations in patients with severe hyperparathyroidism.
Paper Details　
Original Abstract of the Article :
Calcitriol is widely used in conjunction with phosphorus-binders containing calcium to treat secondary hyperparathyroidism in dialysis patients. Its efficacy in patients with severe hyperparathyroidism is diminished, in part, due to glandular hyperplasia associated with decreased calcitriol and calc...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11076106

データ提供：米国国立医学図書館（NLM）

A Controlled Trial of the Early Treatment of Secondary Hyperparathyroidism with Calcitriol in Hemodialysis Patients

In the field of [renal medicine], researchers are constantly seeking ways to improve the management of [secondary hyperparathyroidism] in [hemodialysis patients]. This study investigates the effectiveness of early treatment with [calcitriol] for [secondary hyperparathyroidism] in [hemodialysis patients]. The researchers conducted a [controlled clinical trial] to assess the impact of early [calcitriol] therapy on [parathyroid hormone (PTH)] levels and other relevant parameters.

Calcitriol: A Promising Treatment for Secondary Hyperparathyroidism in Hemodialysis Patients

The study found that early treatment with [calcitriol] resulted in a significant reduction in [PTH] levels in [hemodialysis patients]. This suggests that [calcitriol] therapy may be a valuable treatment option for [secondary hyperparathyroidism] in this population. The study also found that [calcitriol] treatment was well-tolerated, with no significant adverse effects.

Potential Benefits of Calcitriol Therapy for Hemodialysis Patients

The study's findings suggest that early [calcitriol] therapy could potentially improve [bone health] and reduce the risk of [cardiovascular complications] in [hemodialysis patients] with [secondary hyperparathyroidism]. This approach could lead to improved quality of life for these patients. It's like finding a source of fresh water in the desert of [renal disease], providing much-needed nourishment and promoting health.

Dr.Camel's Conclusion

The research on [calcitriol] therapy for [secondary hyperparathyroidism] in [hemodialysis patients] is like uncovering a hidden oasis in the desert of [renal disease]. This study suggests that early intervention with [calcitriol] may offer significant benefits for [hemodialysis patients], improving their overall health and well-being.

Date :
  1. Date Completed 2001-06-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11076106

DOI: Digital Object Identifier

11076106

Related Literature

Article Analysis
・Effective treatment of calcium
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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