Comparison of the systemic effects of fluticasone propionate and budesonide given by dry powder inhaler in healthy and asthmatic subjects.

Author: HarrisonT W, HonourJ, TattersfieldA E, WisniewskiA

Paper Details 
Original Abstract of the Article :
The potential for long term adverse effects from inhaled corticosteroids relates to their systemic absorption, usually assessed from proxy markers in short term studies. When fluticasone propionate and budesonide have been compared in this way the results have been inconsistent. To determine whether...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1136/thorax.56.3.186

データ提供:米国国立医学図書館(NLM)

Inhaled Corticosteroids: A Careful Approach is Essential

Inhaled corticosteroids (ICS), a common treatment for asthma, are like a soothing breeze in the desert of respiratory illness, helping to alleviate symptoms and improve lung function. However, long-term use of ICS can have systemic effects, This study investigates the systemic effects of fluticasone propionate and budesonide, two commonly prescribed ICS. The researchers found that the systemic effects of these drugs varied depending on the subject studied and the marker used to assess systemic absorption. This is like trying to measure the depth of a desert well using different tools – each might provide a different perspective. This study underscores the importance of careful monitoring and consideration of potential systemic effects when prescribing ICS.

A Closer Look at the Systemic Effects of Inhaled Corticosteroids

This study provides valuable insights into the complex interplay between ICS and the body, emphasizing the need for a nuanced approach to their use. By carefully considering the potential systemic effects, clinicians can ensure that patients receive the optimal benefits from these medications while minimizing potential risks. It's like navigating a desert, being aware of the potential hazards and making informed decisions to avoid them.

A Balancing Act in Respiratory Health

The use of ICS requires a careful balance between benefits and risks. While these medications can effectively manage asthma symptoms, understanding their potential systemic effects is crucial. By working closely with your healthcare provider, you can navigate the desert of respiratory health and find the best treatment plan for your individual needs.

Dr.Camel's Conclusion

This study underscores the importance of thoughtful use of medications, even those with proven benefits. By carefully considering the potential systemic effects of ICS, healthcare professionals can help patients navigate the desert of respiratory illness and achieve the best possible outcomes.

Date :
  1. Date Completed 2001-03-22
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

11182010

DOI: Digital Object Identifier

10.1136/thorax.56.3.186

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.