How to treat Helicobacter pylori. First-line, second-line, and future therapies.

Author: MarshallB J, MégraudF

Paper Details 
Original Abstract of the Article :
Numerous trials were performed in the 1990s to define the optimal therapy for Helicobacter pylori infections. The proposed proton-pump inhibitor (PPI)-based and ranitidine bismuth citrate (RBC)-based triple therapies led to satisfactory results. Their first drawback is cost, and, for this reason, ma...See full text at original site
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引用元:
https://doi.org/10.1016/s0889-8553(05)70145-x

データ提供:米国国立医学図書館(NLM)

Treating Helicobacter pylori: A Journey Through Therapies

Helicobacter pylori infection, a common cause of stomach ulcers, has been the subject of extensive research to develop effective treatments. This study delves into the history and evolution of H. pylori treatment, starting with the introduction of proton-pump inhibitor (PPI)-based and ranitidine bismuth citrate (RBC)-based triple therapies. The study highlights the limitations of these first-line therapies, including their cost and the emergence of antimicrobial resistance. The research explores promising alternative approaches, including second-line treatments with antimicrobial agents that H. pylori is less resistant to, and the search for new drugs that are highly effective, nonselective of resistant strains, and without side effects. The authors emphasize the importance of postgenomic studies in developing these new drugs.

Eradicating Helicobacter pylori: A Quest for Optimal Therapies

This study underscores the ongoing battle against Helicobacter pylori infection, a persistent challenge in the world of medicine. The research highlights the need for new drugs that overcome the limitations of current therapies, including cost and resistance. The study's findings, like a map leading through the labyrinth of H. pylori treatment, provide valuable insights into the complexities of this common infection.

Helicobacter pylori: A Common Cause of Stomach Ulcers

H. pylori infection is a prevalent condition that can lead to stomach ulcers. This research, like a guide through the intricate pathways of the digestive system, offers a comprehensive overview of H. pylori treatment strategies. The study emphasizes the importance of research and development in combating this common ailment, reminding us that like the desert's ever-changing landscape, the world of medicine requires constant adaptation and innovation.

Dr.Camel's Conclusion

The quest to eradicate Helicobacter pylori, like a trek across the unforgiving desert, requires perseverance and ingenuity. This research, like a refreshing oasis, highlights the need for effective treatments that overcome the challenges of resistance and cost. As we continue to navigate the complex world of medicine, we must embrace the spirit of exploration and innovation to find solutions for this prevalent infection.

Date :
  1. Date Completed 2001-05-10
  2. Date Revised 2019-11-04
Further Info :

Pubmed ID

11190062

DOI: Digital Object Identifier

10.1016/s0889-8553(05)70145-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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