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Stratified administration of serotonin 5-HT3 receptor antagonists (setrons) for chemotherapy-induced emesis. Economic implications.

Author: BartelS B, HoldsworthM, SanchezL A

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Serotonin 5-HT3 receptor antagonists are effective for preventing chemotherapy-induced emesis (CIE). Dose stratification can improve both clinical and economic outcomes. Strategies for cost-effective use include using lower doses, oral formulations, and guidelines for appropriate use.
Paper Details　
Original Abstract of the Article :
The serotonin 5-HT3 receptor antagonists or 'setrons' have become the standard of care for the prevention of chemotherapy-induced emesis (CIE) and are first-line therapy for acute CIE in healthcare organisations worldwide. However, their superior efficacy versus standard antiemetics comes at a signi...See full text at original site
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引用元：
https://doi.org/10.2165/00019053-200018060-00002

データ提供：米国国立医学図書館（NLM）

Stratified Administration of Serotonin 5-HT3 Receptor Antagonists: A Cost-Effective Approach for Chemotherapy-Induced Emesis

Chemotherapy-induced emesis (CIE) is a common and often debilitating side effect of cancer treatment. This study explores the cost-effectiveness of stratified administration of serotonin 5-HT3 receptor antagonists, known as 'setrons,' for the prevention and treatment of CIE. The authors argue that tailoring setron dosage to the emetogenic potential of the chemotherapy regimen can provide both clinical and economic benefits.

Optimizing Treatment for Chemotherapy-Induced Emesis

This research is like navigating a desert landscape, where resource management is crucial. The authors advocate for a more personalized approach to managing CIE, tailoring setron dosage to match the severity of the emetogenic challenge. This strategy, likened to a wise traveler using water resources wisely, can improve patient outcomes and reduce healthcare costs.

Navigating Chemotherapy Side Effects Effectively

Chemotherapy, a powerful tool against cancer, can sometimes be accompanied by unwelcome side effects. Understanding the effectiveness and cost-effectiveness of different treatment strategies for CIE can empower patients and healthcare providers to make informed decisions, ensuring a smoother journey through cancer treatment.

Dr.Camel's Conclusion

This research emphasizes the importance of tailored treatment approaches for CIE. It's like a desert traveler choosing the right path based on the terrain and resources available. By optimizing setron dosage based on the emetogenic potential of chemotherapy, healthcare providers can improve patient well-being and achieve cost-effective outcomes.

Date :
  1. Date Completed 2001-03-29
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

11227393

DOI: Digital Object Identifier

10.2165/00019053-200018060-00002

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Languages

English

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