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Advances in use of the 5-HT3 receptor antagonists.

Author: WaltonS M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

5-HT3 receptor antagonists, such as ondansetron, granisetron, and dolasetron, are effective in preventing chemotherapy-induced nausea and vomiting. They are considered standard of care for moderately and highly emetogenic chemotherapy.
Paper Details　
Original Abstract of the Article :
Nausea and vomiting continue to rank as important side effects for cancer patients receiving chemotherapy. The class of drugs known as the 5-HT3 receptor antagonists have become widely used for chemotherapy-induced nausea and vomiting, and are considered a standard part of care for moderately- and h...See full text at original site
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引用元：
https://doi.org/10.1517/14656566.1.2.207

データ提供：米国国立医学図書館（NLM）

5-HT3 Receptor Antagonists: A Powerful Weapon Against Chemotherapy-Induced Nausea and Vomiting

This study delves into the realm of chemotherapy-induced nausea and vomiting (CINV), a significant challenge faced by cancer patients undergoing treatment. The research explores the use of 5-HT3 receptor antagonists, a class of drugs that have become a mainstay in CINV prevention. The study reviews the efficacy and safety of these drugs, highlighting their role in improving the quality of life for cancer patients. This research underscores the importance of effective CINV management in enhancing patient well-being during cancer treatment.

A Breakthrough in CINV Management: 5-HT3 Receptor Antagonists

The study emphasizes the significant contribution of 5-HT3 receptor antagonists in managing CINV. These drugs have demonstrated efficacy in preventing both acute and delayed nausea and vomiting, reducing the burden of this debilitating side effect. The research suggests that these drugs are a standard part of care for patients receiving moderately and highly emetogenic chemotherapy. This study highlights the importance of these drugs in improving the quality of life for cancer patients.

Managing CINV: A Multifaceted Approach

While 5-HT3 receptor antagonists have proven effective in managing CINV, it is crucial to remember that a multidisciplinary approach is often necessary. This may involve a combination of drugs, supportive care strategies, and tailored treatment plans. The study emphasizes the need for a holistic approach to CINV management, ensuring optimal patient comfort and well-being throughout cancer treatment. This research underscores the importance of collaboration among healthcare professionals to optimize CINV management.

Dr.Camel's Conclusion

Imagine a desert traveler facing a relentless sandstorm. Just as a well-equipped traveler can navigate the storm with greater ease, 5-HT3 receptor antagonists offer a crucial shield against the unpleasant effects of chemotherapy. By understanding the role of these drugs, we can strive to provide compassionate and effective care for cancer patients, helping them endure the journey of treatment with greater comfort and dignity.

Date :
  1. Date Completed 2001-04-05
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

11249543

DOI: Digital Object Identifier

10.1517/14656566.1.2.207

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Languages

English

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