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Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study.

Author: BelmonteA, CavaliereC, CilibertoE, FioccaR, FrandinaC, GiglioA, LuzzaF, PalloneF, SaccàN, TrimboliV

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A proton pump inhibitor-based triple therapy regimen may be more effective than a ranitidine bismuth citrate-based dual therapy regimen in eradicating Helicobacter pylori in patients with duodenal ulcer, though further research is needed to confirm this.
Paper Details　
Original Abstract of the Article :
The optimal treatment regimen for eradication of Helicobacter pylori in patients with duodenal ulcer has yet to be determined. Based on a search of MEDLINE, no studies have been performed comparing a proton pump inhibitor-based triple therapy regimen with a ranitidine bismuth citrate (RBC)-based dua...See full text at original site
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引用元：
https://doi.org/10.1016/s0149-2918(01)80025-4

データ提供：米国国立医学図書館（NLM）

Eradicating Helicobacter pylori: A Battle in the Desert of Gastric Health

Helicobacter pylori is a bacterium that can cause peptic ulcers and other gastrointestinal problems. This study explores the effectiveness of two different treatment regimens for eradicating this persistent bacterium in patients with duodenal ulcers. The researchers compared the outcomes of a lansoprazole-based triple therapy regimen with a ranitidine bismuth citrate (RBC)-based dual therapy regimen, both containing clarithromycin, providing valuable insights into the optimal treatment strategies for managing H. pylori infection.

The Desert of Gastric Infections: A Comparative Study of Treatment Regimens

The study's findings provide valuable insights into the relative effectiveness of different treatment regimens for eradicating H. pylori in patients with duodenal ulcers. This research guides healthcare providers in selecting the most appropriate therapy for individual patients, optimizing treatment outcomes and improving patient well-being.

The Oasis of Digestive Health: Choosing the Right Treatment for H. pylori

The study highlights the importance of understanding the specific characteristics of H. pylori infection and selecting the most appropriate treatment regimen for each individual patient. Just as a camel navigates the desert landscape, healthcare providers must carefully select the right tools to overcome this persistent foe.

Dr. Camel's Conclusion

This study provides valuable insights into the best approach for battling H. pylori infections. Just as a camel adapts to the harsh desert environment, healthcare providers must carefully consider individual patient needs and choose the most effective treatment strategy to eradicate this persistent bacterium. This research guides us toward a clearer understanding of the desert of gastric health, helping us to develop better treatments and protect patient well-being.

Date :
  1. Date Completed 2001-10-11
  2. Date Revised 2019-09-21
Further Info :

Pubmed ID

11394734

DOI: Digital Object Identifier

10.1016/s0149-2918(01)80025-4

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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