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Dihydroergotamine nasal spray in the treatment of acute migraine.

Author: HeringR, KorczynA D, KuritzkyA, TrevesT A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Dihydroergotamine (DHE) nasal spray was found to be well tolerated and to have dose-dependent efficacy in migraine. Patients taking DHE used less rescue medications, and the tolerability of the drug was assessed as good by 94% of the patients.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of dihydroergotamine (DHE) nasal spray in patients suffering from common or classical migraine. METHODS: In a double-blind parallel-group study, 52 outpatients with migraine were randomly allocated to DHE nasal spray or to placebo. Two puffs, one in ea...See full text at original site
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引用元：
https://doi.org/10.1046/j.1526-4610.1998.3808614.x

データ提供：米国国立医学図書館（NLM）

Dihydroergotamine Nasal Spray: A Potential Oasis in the Desert of Migraine

Migraine, a debilitating neurological condition, affects millions worldwide. This research investigates the efficacy and safety of dihydroergotamine (DHE) nasal spray in treating acute migraine attacks. The study aims to evaluate the effectiveness of DHE nasal spray compared to placebo.

DHE Nasal Spray: A Potential Weapon Against the Migraine Desert

The study found that DHE nasal spray, particularly at a dose of 1 mg, tended to provide better relief from migraine symptoms compared to placebo, although the effect was not statistically significant. The study also observed a dose-dependent reduction in the use of rescue medications.

Navigating the Migraine Landscape: Exploring Treatment Options

This research provides valuable insights into the potential of DHE nasal spray as a treatment option for acute migraine attacks. While further research is needed to confirm its efficacy and optimize its use, DHE nasal spray offers a potential avenue for managing this challenging condition.

Dr.Camel's Conclusion

This research explores the potential of DHE nasal spray as a weapon against the desert of migraine pain. While further research is needed to confirm its efficacy, DHE nasal spray offers a potential oasis of relief for those struggling with migraine attacks. The study highlights the importance of exploring various treatment options to find the most effective and personalized approaches for managing this debilitating condition.

Date :
  1. Date Completed 2001-07-26
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

11398305

DOI: Digital Object Identifier

10.1046/j.1526-4610.1998.3808614.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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