Effects on 24-hour intragastric pH: a comparison of lansoprazole administered nasogastrically in apple juice and pantoprazole administered intravenously.

Author: ChiuY L, FrestonJ, LukasikN, PanW J, TäubelJ

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare the 24-h intragastric pH effects of lansoprazole, 30 mg administered nasogastrically, with pantoprazole, 40 mg administered i.v. METHODS: Healthy adults were enrolled in an open label, two-way crossover, single-center study. Thirty milligrams of lansoprazole (administered naso...See full text at original site
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引用元:
https://doi.org/10.1111/j.1572-0241.2001.03939.x

データ提供:米国国立医学図書館(NLM)

Lansoprazole: An Effective Alternative to IV Pantoprazole

This research investigates the effectiveness of lansoprazole, a proton pump inhibitor, when administered nasogastrically (through a tube in the nose) compared to intravenous pantoprazole. The researchers studied healthy volunteers who received either lansoprazole or pantoprazole for five consecutive days, measuring intragastric pH levels over 24 hours. They found that lansoprazole administered nasogastrically was significantly more effective in controlling intragastric pH than intravenous pantoprazole. These results suggest that lansoprazole could be a viable alternative for patients who are unable to swallow solid medications.

Lansoprazole: A Promising Option for Patients

This study offers a promising alternative for patients who struggle to swallow medications. The finding that lansoprazole, when administered nasogastrically, is as effective as intravenous pantoprazole provides valuable information for healthcare providers when treating patients with difficulty swallowing.

Expanding Treatment Options: A Benefit for Patients

This research underscores the importance of finding alternative treatment options for patients with specific needs. By exploring different administration routes, healthcare providers can provide effective treatment for patients who may have difficulty swallowing or require specific modes of drug delivery. This approach can improve patient comfort and treatment outcomes.

Dr.Camel's Conclusion

Just as a camel adapts to navigating challenging terrain, healthcare professionals need to be adaptable in their approaches to patient care. This research highlights the benefits of exploring different treatment options to ensure that patients receive the best possible care, regardless of their individual needs.

Date :
  1. Date Completed 2001-08-30
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

11467632

DOI: Digital Object Identifier

10.1111/j.1572-0241.2001.03939.x

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SNS
PICO Info
in preparation
Languages

English

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