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[Apropos of atypical melancholia with Sustiva (efavirenz)].

Author: DanionJ M, HalleguenO, LangJ M, LangJ P, PicardA

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This article discusses the psychiatric side effects of efavirenz, a medication used to treat HIV. Efavirenz can cause a variety of psychiatric side effects, including nightmares, hallucinations, and depression.
Paper Details　
Original Abstract of the Article :
The treatment of HIV infection has changed dramatically in recent years as a result of the development of new drugs which allows a variety of multitherapy combinations more adapted to patients' needs and thereby improving compliance. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. In ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/11488260

データ提供：米国国立医学図書館（NLM）

Efavirenz: A Double-Edged Sword in HIV Treatment

The fight against HIV/AIDS is a constant struggle, like navigating a vast desert in search of a cure. Efavirenz, a non-nucleoside reverse transcriptase inhibitor, has emerged as a powerful weapon in this fight, but it can also have unexpected side effects. This article explores the potential psychiatric complications associated with efavirenz treatment, focusing on a case of atypical melancholia with marked cognitive disorders. The authors describe the case of Mister H., who experienced two severe melancholic episodes while taking efavirenz, which resolved only after discontinuing the medication.

Navigating the Psychological Desert of HIV Treatment

This case highlights the importance of careful monitoring for psychiatric side effects in patients taking efavirenz. While this medication offers a valuable tool in managing HIV, its potential to induce mood disorders and cognitive impairment requires vigilance and prompt intervention. The article underscores the need for a multidisciplinary approach to HIV care, involving clinicians, psychiatrists, and neuropsychologists to address the complexities of treatment and manage potential side effects.

Finding Balance in the Desert of HIV Treatment

This report serves as a reminder of the complex interplay between physical and mental health in HIV treatment. It emphasizes the importance of careful patient monitoring, early identification of potential side effects, and a collaborative approach to managing both physical and mental well-being.

Dr.Camel's Conclusion

This case illustrates the potential for efavirenz to induce psychiatric side effects, emphasizing the importance of careful monitoring and management. While efavirenz offers a valuable tool in HIV treatment, it's crucial to recognize and address any emerging mental health challenges. A multidisciplinary approach to HIV care can help navigate the complexities of treatment and ensure the best possible outcomes for patients.

Date :
  1. Date Completed 2001-10-04
  2. Date Revised 2020-12-08
Further Info :

Pubmed ID

11488260

DOI: Digital Object Identifier

11488260

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