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Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial.

Author: GalimbertiV, LuiniA, MarianiL, MarubiniE, SalvadoriB, VeronesiP, VeronesiU, ZucaliR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Radiotherapy appears indicated after breast-conserving surgery in patients up to 55 years of age, those with positive axillary nodes, and those with extensive intraductal component at histology. Radiotherapy may be avoided in patients older than 65 and may be optional in women aged 56-65 years with negative nodes.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Breast-conserving surgery followed by radiotherapy is a widely accepted form of treatment in patients with breast cancer of limited extent. Many attempts have been made to identify subgroups of patients who might avoid radiotherapy. PATIENTS AND METHODS: Between 1987 and 1989, 579 women...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11521809

データ提供：米国国立医学図書館（NLM）

Radiotherapy After Breast-Conserving Surgery: A Balancing Act in Cancer Treatment

This research delves into the effectiveness of radiotherapy after breast-conserving surgery, like a delicate dance in the desert of cancer treatment, seeking the best balance between effectiveness and minimal side effects. The researchers conducted a randomized trial, comparing two groups of women with breast cancer to determine the optimal course of treatment.

Finding the Right Path: Tailoring Breast Cancer Treatment

The study found that radiotherapy after breast-conserving surgery significantly reduces the risk of tumor recurrence, much like building a sturdy wall in the desert to prevent sand encroachment. However, the researchers also acknowledge the importance of considering individual patient factors, such as age and tumor characteristics, when deciding whether radiotherapy is necessary.

Making Informed Decisions: Navigating the Desert of Breast Cancer Treatment

This research highlights the need for personalized approaches to breast cancer treatment, taking into account the unique characteristics of each patient and the potential risks and benefits of different treatment options. It's like choosing the best route through a desert, considering the terrain and the resources available. By carefully weighing the factors involved, healthcare providers can create a treatment plan that offers the best chance of success while minimizing potential side effects.

Dr.Camel's Conclusion

Radiotherapy after breast-conserving surgery can be an effective tool in the fight against breast cancer. However, it's not a one-size-fits-all approach. By carefully evaluating individual patient factors, we can make informed decisions and navigate the desert of breast cancer treatment with greater confidence.

Date :
  1. Date Completed 2002-02-05
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

11521809

DOI: Digital Object Identifier

S0923-7534(19)54188-6

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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