Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal, flare, and itch in human skin.

Author: BoutsioukiP, ChurchM K, CloughG F

Paper Details 
Original Abstract of the Article :
BACKGROUND: This randomized, double-blind, crossover study compared the effects of the R-enantiomer of cetirizine, levocetirizine, with those of loratadine on the wheal, flare, and itch response to histamine in human skin. METHODS: Levocetirizine (5 mg), loratadine (10 mg), or placebo was taken ora...See full text at original site
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引用元:
https://doi.org/10.1034/j.1398-9995.2001.00204.x

データ提供:米国国立医学図書館(NLM)

Levocetirizine vs. Loratadine: A Camel's Journey Through Allergy Relief

This research explores the vast and often itchy desert of [allergic reactions] and the effectiveness of different antihistamines in providing relief. The researchers conducted a [randomized, double-blind, crossover study] to compare the effects of [levocetirizine] and [loratadine] on [histamine-induced wheal, flare, and itch] in healthy volunteers. Their findings revealed that [levocetirizine (5 mg) significantly reduced wheal, flare, and itch] compared to placebo, while [loratadine (10 mg) showed variable and non-significant effects].

The Camel's Insights: What Does This Mean?

The study suggests that [levocetirizine is a more potent inhibitor of histamine-induced reactions] compared to loratadine. The researchers' meticulous design, like a camel carefully navigating a desert of allergens, provides valuable information for clinicians seeking the most effective antihistamines for their patients.

The Camel's Health Tips

If you suffer from allergies, it's essential to consult a healthcare professional for personalized advice on managing your condition. They can help you determine the most appropriate antihistamine and other treatment options. Remember, a wise camel always seeks expert guidance to navigate the desert of allergies.

Dr. Camel's Conclusion

This research, like a camel's journey through a desert of itchy challenges, highlights the importance of choosing the right antihistamine for allergy relief. Levocetirizine appears to be a more effective option than loratadine, offering greater relief from histamine-induced reactions. Remember, a wise camel always seeks the most effective and comforting remedies to navigate the desert of allergies.

Date :
  1. Date Completed 2001-11-01
  2. Date Revised 2021-04-09
Further Info :

Pubmed ID

11576078

DOI: Digital Object Identifier

10.1034/j.1398-9995.2001.00204.x

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SNS
PICO Info
in preparation
Languages

English

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