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Effects of amphotericin B gargles on oral colonization of Candida albicans in asthmatic patients on steroid inhalation therapy.

Author: FukushimaC, KawanoT, KohnoS, MatsuoN, MatsuseH, MitsutaK, ObaseY, ShimodaT, TomariS

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This article discusses the side effects of inhaled steroids, which are commonly used for bronchial asthma. Although side effects are rare, oral discomfort and candidiasis are clinically significant. The use of a spacer and water gargling can help prevent these complications, but they may not be effective in all patients.
Paper Details　
Original Abstract of the Article :
Early use of inhaled steroids is recommended for bronchial asthma. The side effects are rare, but oral discomfort and candidiasis are clinically important complications. Most previous studies reported that the use of spacer and water gargling was necessary to prevent oral complications. However, in ...See full text at original site
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引用元：
https://doi.org/10.1159/000050552

データ提供：米国国立医学図書館（NLM）

Candida Albicans: A Potential Side Effect of Inhaled Steroid Therapy

Inhaled steroids are an effective treatment for bronchial asthma, but they can have side effects, including oral discomfort and candidiasis. This study investigates the use of amphotericin B gargles in preventing oral colonization by Candida albicans in asthmatic patients receiving inhaled steroid therapy. The researchers evaluated the effectiveness of amphotericin B gargles in reducing oral colonization by Candida albicans, exploring potential strategies for preventing this common side effect.

Amphotericin B Gargles: A Potential Solution for Oral Candidiasis

The study highlights the potential of amphotericin B gargles in reducing oral colonization by Candida albicans. The research findings suggest that amphotericin B gargles may be an effective strategy for preventing oral candidiasis in asthmatic patients receiving inhaled steroid therapy. Further research is needed to confirm these findings and to evaluate the long-term efficacy and safety of amphotericin B gargles in this population.

Managing Inhaled Steroid Therapy: A Balancing Act

The study underscores the importance of managing potential side effects associated with inhaled steroid therapy. The research findings suggest that amphotericin B gargles may be a valuable tool for preventing oral candidiasis, ensuring a more comfortable and effective treatment experience for patients receiving inhaled steroids.

Dr.Camel's Conclusion

Like a camel adapting to the harsh desert environment, patients with asthma must navigate the potential side effects of inhaled steroid therapy. This study explores the use of amphotericin B gargles in preventing oral candidiasis, a common side effect of inhaled steroids. While further research is needed, this approach may offer a potential solution for reducing oral colonization by Candida albicans, allowing patients to experience the benefits of inhaled steroids with fewer complications.

Date :
  1. Date Completed 2001-12-13
  2. Date Revised 2017-11-01
Further Info :

Pubmed ID

11694807

DOI: Digital Object Identifier

10.1159/000050552

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Languages

English

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