Side Effects of beclomethasone oral inhalation: A Synthesis of Findings from 31 Studies

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This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Side Effects of beclomethasone oral inhalation: A Synthesis of Findings from 31 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

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This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Main Research Findings

Beclomethasone oral inhalation is a commonly used medication for the treatment of asthma and chronic obstructive pulmonary disease (COPD). 6 The most frequent side effect of this drug is oropharyngeal disorders, which may negatively affect adherence to treatment. 6

Beclomethasone oral inhalation is considered to be safer than other inhaled steroids, with less systemic absorption and fewer side effects. 8

The use of a spacer with a metered-dose inhaler is recommended for beclomethasone oral inhalation to reduce oropharyngeal deposition and increase lung deposition. 29

Reasons for Side Effects

Beclomethasone oral inhalation can adhere to the oropharyngeal mucosa during inhalation, potentially causing local inflammation. 6 Some of the medication may be absorbed systemically, causing side effects.

Common Side Effects

Oropharyngeal Candidiasis

Oropharyngeal candidiasis has been reported as a side effect of beclomethasone oral inhalation. 19 13 7

Dysphonia

Dysphonia has been reported as a side effect of beclomethasone oral inhalation. 31 20

Oral Thrush

Oral thrush has been reported as a side effect of beclomethasone oral inhalation. 19

Osteoporosis

Osteoporosis has been reported as a side effect of beclomethasone oral inhalation. 8

Adrenal Suppression

Adrenal suppression has been reported as a side effect of beclomethasone oral inhalation. 8

Glaucoma

Glaucoma has been reported as a side effect of beclomethasone oral inhalation. 8

Side Effect Countermeasures

Oropharyngeal Candidiasis

To prevent oropharyngeal candidiasis, it is recommended to rinse your mouth after inhalation. 19 7

Dysphonia

To prevent dysphonia, it is recommended to rinse your mouth after inhalation. 31

Osteoporosis

To prevent osteoporosis, it is recommended to maintain calcium and vitamin D intake. 8

Adrenal Suppression

To prevent adrenal suppression, regular blood tests are necessary for monitoring. 8

Glaucoma

To prevent glaucoma, regular eye exams are necessary. 8

Comparison Between Studies

Commonalities Between Studies

Multiple studies have confirmed that beclomethasone oral inhalation is effective in treating asthma. These studies have also reported oropharyngeal candidiasis and dysphonia as side effects of beclomethasone oral inhalation.

Differences Between Studies

The incidence and severity of side effects from beclomethasone oral inhalation may vary depending on the study. This could be due to factors such as the patient population studied and the dosage of beclomethasone used.

Points to Note Regarding Practical Application

Beclomethasone oral inhalation is an effective medication for treating asthma and COPD. However, it is important to be aware of the risks of side effects and to follow the proper usage instructions. If you experience any side effects, such as oropharyngeal candidiasis or dysphonia, consult a doctor.

Current Limitations of Research

There is still insufficient research on the long-term use of beclomethasone oral inhalation. Therefore, further research is needed on the risks and safety of long-term use.

Future Research Directions

Research is needed to evaluate the risks and safety of long-term use of beclomethasone oral inhalation. Additionally, research is needed on methods to reduce side effects and methods of administration to reduce the risk of side effects.

Conclusion

Beclomethasone oral inhalation is an effective medication for treating asthma and COPD, but it is important to be aware of the risk of side effects and follow the proper usage instructions. If you experience any side effects, consult a doctor.

Keywords
Benefit Keywords
Allergic rhinosinusitis treatment
Asthma treatment
COPD treatment
1
Asthma treatment
2
Asthma treatment
3
Lung disorder treatment
Reduced side effects
4
Asthma
Rescue treatment
5
Asthma treatment
COPD treatment
6
Allergic rhinitis treatment
7
Asthma treatment
8
Asthma exacerbation treatment
9
Asthma treatment
10
Prophylactic treatment of asthma
11
Asthma control
12
Asthma treatment
13
Fluticasone more effective than others
14
CEP improvement
15
Treats pulmonary hemosiderosis
16
Asthma control
17
Improved airway caliber
18
asthma treatment
21
Asthma treatment
22
Asthma treatment
23
Improved asthma control
24
Improved asthma symptoms
Improved lung function
Reduced asthma symptoms
26
Improved understanding of pulmonary sarcoidosis treatment
27
Allergic rhinitis relief
Nasal congestion reduction
28
Asthma control
Reduced side effects
29
High local effects
Low systemic bioavailability
Persistent asthma treatment
31
Risk Keywords
Diabetes control
Diabetes risk
1
Glucocorticoid side effects
2
Oropharyngeal disorders
6
Esophageal candidiasis
7
Avascular necrosis
8
Side effects
9
Oral side effects
10
Oral candidiasis
13
Fluticasone higher risk of pharyngitis
14
CEP relapse
CEP worsening
corticosteroid side effects
15
Steroid side effects
17
Pharyngitis
Side effects
18
Candidiasis
Oral discomfort
19
Cough
Dysphonia
Hoarseness
Oral candidiasis
Perioral dermatitis
Thirsty feeling
Tongue hypertrophy
20
Questionable significance
22
Side effects
23
Deleterious side effects of steroids
Unclear benefit of corticosteroids
Unpredictable course
25
Adverse effects
26
Drowsiness
Headache
28
Adrenal suppression
Bone mineral density reduction
Growth retardation
29
Dysphonia
Oral candidiasis
31
Literature analysis of 31 papers
Positive Content
26
Neutral Content
1
Negative Content
4
Article Type
3
3
10
16
31
3.

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children.

Author: KewKayleigh M, KarnerCharlotta, MindusStephanie M, FerraraGiovanni

Asthma treatment

Asthma is a chronic lung condition with recurring episodes of wheezing, chest tightness, and coughing. Inhaled medications are often effective in controlling symptoms, preventing complications, and improving quality of life. While some medications are taken regularly and others for symptom relief, a single inhaler containing both a steroid and a bronchodilator is available (SiT or SMART therapy). This treatment may improve adherence to medication, reducing symptoms and exacerbations, but it's unclear whether it increases side effects from the steroid.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

5.

Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.

Author: MartinezFernando D, ChinchilliVernon M, MorganWayne J, BoehmerSusan J, LemanskeRobert F, MaugerDavid T, StrunkRobert C, SzeflerStanley J, ZeigerRobert S, BacharierLeonard B, BadeElizabeth, CovarRonina A, FriedmanNoah J, GuilbertTheresa W, Heidarian-RaissyHengameh, KellyH William, Malka-RaisJonathan, MellonMichael H, SorknessChristine A, TaussigLynn

Asthma
Rescue treatment

This study evaluated the effectiveness of using an inhaled corticosteroid (beclomethasone dipropionate) as rescue treatment for children with mild persistent asthma experiencing exacerbations despite good day-to-day control. The results suggest that rescue treatment with inhaled corticosteroids may be beneficial in managing asthma exacerbations in children.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Prevalence and associated factors of oropharyngeal side effects in users of inhaled corticosteroids in a real-life setting.

Author: MolimardMathieu, Le GrosVincent, RobinsonPhilip, BourdeixIsabelle

Asthma treatment
COPD treatment
Oropharyngeal disorders

Oropharyngeal disorders are common in users of inhaled corticosteroids (ICS) with a prevalence of 34.7%. COPD indication, higher nominal daily dose, decreased adherence, and the use of fluticasone were associated with an increased risk of oropharyngeal disorders.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

[A case of the esophageal candidiasis supposedly caused by rhinenchysis steroid chronic administration before sleep].

Author: ShutoHiroshi, NoguchiHisashi, NishikataHikaru, TakizawaKenji, ShutoChizuru, NagataMakoto, TerashiYoshinori, YamaguchiMichiya, TakizawaTakao, WatanabeKensuke, TosakaKaoru, OkanoMasahiko, KoizumiAkira

Allergic rhinitis treatment
Esophageal candidiasis

This report describes a case of esophageal candidiasis in a 69-year-old female patient with chronic perennial allergic rhinitis who had been using inhaled Beclometasone dipropionate (BDP) for two years. The patient developed dysphagia and was diagnosed with pharyngitis and esophageal candidiasis. The patient did not report using the BDP before the endoscopy as she did not associate it with her symptoms. Treatment involved stopping BDP and using Azunol mouthwash, which resulted in an improvement in the patient's symptoms within two weeks. The esophageal candidiasis became Grade I (mild grade) after a month and a half. The patient did not report any subjective symptoms such as nasal obstruction or dysphagia.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

8.

Aseptic femoral head necrosis in a patient receiving long term courses of inhaled and intranasal corticosteroids.

Author: KarkouliasKiriakos, CharokoposNikos, KaparianosAlexander, SampsonasFotis, TsiamitaMaria, SpiropoulosKostas

Asthma treatment
Avascular necrosis

A rare case of avascular osteonecrosis of the femoral head associated with long-term inhaled fluticasone propionate and intranasal triamcinolone acetonide is reported. While fluticasone is generally considered safer than other inhaled steroids due to its lower systemic bioavailability, potential systemic side effects like adrenal insufficiency, growth suppression, glaucoma, and osteoporosis remain a concern.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

9.

Pharmacological strategies for self-management of asthma exacerbations.

Author: ReddelH K, BarnesD J,

Asthma exacerbation treatment
Side effects

Pharmacological strategies for self-management of asthma exacerbations in adults were reviewed. Oral corticosteroids are well-established for severe exacerbations, while high-dose inhaled corticosteroids may be beneficial for some patients.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

10.

The dose-response characteristics of inhaled corticosteroids when used to treat asthma: an overview of Cochrane systematic reviews.

Author: AdamsN P, JonesP W

Asthma treatment
Oral side effects

Inhaled corticosteroids are a cornerstone treatment for asthma. Different doses of beclometasone dipropionate, budesonide, and fluticasone propionate have different efficacy levels, with high doses of fluticasone having a higher risk of oral side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

11.

Inhaled ciclesonide versus inhaled budesonide or inhaled beclomethasone or inhaled fluticasone for chronic asthma in adults: a systematic review.

Author: DyerMatthew J, HalpinDavid M G, SteinKen

Prophylactic treatment of asthma

This systematic review aimed to compare the effectiveness and safety of ciclesonide, a new inhaled corticosteroid, to other commonly prescribed inhaled corticosteroids (beclomethasone dipropionate, budesonide, and fluticasone propionate) in people with asthma.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

12.

Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma.

Author: GreenstoneI R, Ni ChroininM N, MasseV, DanishA, MagdalinosH, ZhangX, DucharmeF M

Asthma control

Two main treatment options are recommended for asthmatic patients inadequately controlled on inhaled corticosteroids or those with moderate persistent asthma: the combination of a long-acting inhaled beta2 agonist (LABA) with inhaled corticosteroids (ICS) or use of a higher dose of inhaled corticosteroids.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

13.

Salivary IgA and oral candidiasis in asthmatic patients treated with inhaled corticosteroid.

Author: FukushimaChizu, MatsuseHiroto, SaekiSachiko, KawanoTetsuya, MachidaIkuko, KondoYuki, KohnoShigeru

Asthma treatment
Oral candidiasis

Inhaled corticosteroids are used to treat asthma. Oral candidiasis is a potential side effect of inhaled corticosteroids and may be related to deficiencies in salivary IgA.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

14.

Inhaled fluticasone versus inhaled beclomethasone or inhaled budesonide for chronic asthma.

Author: AdamsN, BestallJ M, LassersonT J, JonesP W

Fluticasone more effective than others
Fluticasone higher risk of pharyngitis

Fluticasone propionate (FP) given at half the daily dose of beclomethasone or budesonide resulted in small improvements in measures of airway caliber, but it may have a higher risk of causing side effects when given at the same daily dose.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

16.

[Inhaled corticosteroids in idiopathic pulmonary hemosiderosis: 2 cases].

Author: Ben HalimaNabil, KarrayAbderrahmen, KrichenAnas, FekiHichem, Ben SalahMounir, ChabchoubImène, HachichaMongia, MahfoudhAbdelmajid, TrikiAli

Treats pulmonary hemosiderosis

Idiopathic pulmonary hemosiderosis is a rare condition that is characterized by bleeding into the lungs and pulmonary fibrosis. This study describes two cases of idiopathic pulmonary hemosiderosis that were successfully treated with inhaled beclomethasone dipropionate and low-dose oral prednisolone.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : French

17.

The role of corticosteroids in the management of childhood asthma.

Author: van Asperen PeterP, MellisCraig M, SlyPeter D,

Asthma control
Steroid side effects

Inhaled corticosteroids are effective for treating asthma in children, while systemic corticosteroids are used for acute asthma attacks.

GuidelineRecommendations and best practices developed by experts for healthcare professionals to refer to when making clinical judgments and providing care.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Practice GuidelineGuidelines and recommendations for the diagnosis and treatment of specific medical conditions in medical practice.

Language : English

18.

Fluticasone versus beclomethasone or budesonide for chronic asthma.

Author: AdamsN, BestallJ M, JonesP W

Improved airway caliber
Pharyngitis
Side effects

Fluticasone given at half the daily dose of beclomethasone or budesonide leads to small improvements in measures of airway calibre, but it appears to have a higher risk of causing side-effects when given at the same daily dose.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

19.

Effects of amphotericin B gargles on oral colonization of Candida albicans in asthmatic patients on steroid inhalation therapy.

Author: FukushimaC, ShimodaT, KawanoT, TomariS, MitsutaK, ObaseY, MatsuoN, MatsuseH, KohnoS

Candidiasis
Oral discomfort

This article discusses the side effects of inhaled steroids, which are commonly used for bronchial asthma. Although side effects are rare, oral discomfort and candidiasis are clinically significant. The use of a spacer and water gargling can help prevent these complications, but they may not be effective in all patients.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

20.

Local side-effects of inhaled corticosteroids in asthmatic children: influence of drug, dose, age, and device.

Author: DubusJ C, MarguetC, DeschildreA, MelyL, Le RouxP, BrouardJ, HuiartL,

Cough
Dysphonia
Hoarseness
Oral candidiasis
Perioral dermatitis
Thirsty feeling
Tongue hypertrophy

Local side-effects of inhaled corticosteroids (ICS) are common in asthmatic children of all ages, with coughing being the most frequent. The device used for inhalation, particularly spacer devices, was the most influential factor.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : English

21.

Improved safety with equivalent asthma control in adults with chronic severe asthma on high-dose fluticasone propionate.

Author: BerendN, KellettB, KentN, SlyP D,

asthma treatment

This study compared the efficacy and safety of fluticasone propionate (FP) with beclomethasone dipropionate (BDP) and budesonide (BUD) in adult asthmatics requiring high doses of inhaled corticosteroids. FP was found to be as effective as BDP and BUD at high doses, with a similar safety profile.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

22.

Beclomethasone at different doses for chronic asthma (review).

Author: AdamsN, BestallJ, JonesP

Asthma treatment
Questionable significance

Beclomethasone dipropionate (BDP) appears to demonstrate a shallow dose response effect in long-term asthma for some efficacy outcomes over a range of daily doses from 400 mcg/d to 1600 mcg/d.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

23.

Inhaled vs oral steroids for adults with chronic asthma.

Author: MashB, BheekieA, JonesP W

Asthma treatment
Side effects

A daily dose of prednisolone 7.5-10 mg/day appears to be equivalent to moderate-high dose inhaled corticosteroids for adults with chronic asthma. Side-effects may be present on low doses, so the lowest effective dose should be prescribed if oral steroids are necessary.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

24.

Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group.

Author: TamaokiJ, KondoM, SakaiN, AoshibaK, TagayaE, NakataJ, IsonoK, NagaiA

Improved asthma control

Suplatast tosilate, a selective Th2 cytokine inhibitor, improved pulmonary function and symptom control in patients with steroid-dependent asthma. The treatment allowed a decrease in inhaled corticosteroid dose without significant side-effects, though improvements in pharmacokinetics are needed.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

25.

Corticosteroids for pulmonary sarcoidosis.

Author: ParamothayanN S, JonesP W

Deleterious side effects of steroids
Unclear benefit of corticosteroids
Unpredictable course

Pulmonary sarcoidosis is a common condition with unpredictable outcomes. While corticosteroids are often used to treat it, doctors don't agree on when, how much, or for how long they should be used. Since long-term use of corticosteroids can have serious side effects, it's important to know if they provide any lasting benefits for pulmonary sarcoidosis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

26.

Inhaled vs oral steroids for adults with chronic asthma.

Author: MashB, BheekieA, JonesP W

Improved asthma symptoms
Improved lung function
Reduced asthma symptoms
Adverse effects

A daily dose of prednisolone 7.5-10 mg/day appears to be equivalent to moderate-high dose inhaled corticosteroids. Inhaled steroids appear more effective than alternate day doses of prednisolone.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

27.

Corticosteroids for pulmonary sarcoidosis.

Author: ParamothayanN S, JonesP W

Improved understanding of pulmonary sarcoidosis treatment

Pulmonary sarcoidosis is a common condition with an unpredictable course. While corticosteroids (oral or inhaled) are often used to treat it, there is no agreement on when, how much, or how long to use them. Since long-term corticosteroid use can have negative side effects, researchers are investigating whether these medications provide any lasting benefit for pulmonary sarcoidosis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

28.

Efficacy and safety of azelastine nasal spray for the treatment of allergic rhinitis.

Author: GoldenS J, CraigT J

Allergic rhinitis relief
Nasal congestion reduction
Drowsiness
Headache

Azelastine nasal spray is an effective treatment for allergic rhinitis. It has a rapid onset, long duration of action, and minimal systemic side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

29.

Comparative efficacy and safety of inhaled corticosteroids in asthma.

Author: JacksonL D, PolygenisD, McIvorR A, WorthingtonI

Asthma control
Reduced side effects
Adrenal suppression
Bone mineral density reduction
Growth retardation

Inhaled corticosteroids are effective for asthma, but long-term use can cause side effects. This review recommends maximum daily doses for adults and children to avoid serious side effects like growth retardation, adrenal suppression, bone mineral density loss, and cataract formation.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

30.

Effects of inhaled corticosteroid on bone turnover in children with bronchial asthma.

Author: ChayO M, GohA, LimW H, LeongK H, LouJ

Inhaled corticosteroids (ICS) are commonly used to treat asthma. This study found that 6 months of ICS therapy (mean dose 0.4 mg/day) did not have a significant adverse effect on bone metabolism in asthmatic children.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

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