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Effects of short-term oral acitretin therapy on peripheral nerve function: a prospective neurological and neurophysiological study.

Author: ChroniE, GeorgiouS, MonastirliA, PaschalisC, TsambaosD

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the effects of oral acitretin therapy on peripheral nerve function in patients with keratinization disorders. The study found that acitretin can cause dysfunction of sensory nerve fibers, although this dysfunction remained subclinical. The study recommends that neurological and neurophysiological evaluation of peripheral nerves be routinely performed in patients receiving oral acitretin.
Paper Details　
Original Abstract of the Article :
The aim of the present prospective study was to substantiate possible side effects of short-term oral acitretin therapy (1 mg/kg/day) on peripheral nerve function of 13 patients with severe keratinization disorders. Clinical neurological examination before and 1 and 3 months after onset of treatment...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1080/000155501317208372

データ提供：米国国立医学図書館（NLM）

Acitretin and Peripheral Nerve Function: Navigating the Desert of Side Effects

Acitretin is a medication used to treat severe skin conditions, but like a desert journey, it can have unexpected side effects. This study investigates the impact of short-term oral acitretin therapy on peripheral nerve function.

The Desert of Side Effects

The study found that oral acitretin therapy can lead to dysfunction of sensory nerve fibers in some individuals. This is like encountering a hidden sandstorm in the desert, potentially affecting the body's sensory pathways and disrupting the normal flow of information.

Navigating the Challenges

The study highlights the importance of monitoring peripheral nerve function in patients receiving acitretin therapy. This is like carrying a compass and map through the desert, ensuring that we are aware of potential obstacles and can take necessary precautions.

Dr. Camel's Conclusion

This study emphasizes the need for a careful and comprehensive approach to acitretin therapy, recognizing that while it can be beneficial, potential side effects must be carefully considered and managed. We must be vigilant in navigating the desert of potential side effects, ensuring the safety and well-being of patients.
Date :
  1. Date Completed 2002-09-03
  2. Date Revised 2019-01-18
Further Info :

Pubmed ID

11859946

DOI: Digital Object Identifier

10.1080/000155501317208372

Related Literature

Article Analysis
・Effects of acitretin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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