Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs.

Author: BlackDennis M, CummingsSteven R, EnsrudKristine, GenantHarry K, HarrisFran, KarpfDavid B, LaCroixAndrea Z

Paper Details 
Original Abstract of the Article :
PURPOSE: To estimate how much the improvement in bone mass accounts for the reduction in risk of vertebral fracture that has been observed in randomized trials of antiresorptive treatments for osteoporosis. METHODS: After a systematic search, we conducted a meta-analysis of 12 trials to describe th...See full text at original site
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引用元:
https://doi.org/10.1016/s0002-9343(01)01124-x

データ提供:米国国立医学図書館(NLM)

Strengthening Bones, Reducing Fractures: Antiresorptive Drugs

The world of [osteoporosis] is constantly seeking new ways to build stronger bones and prevent fractures. This study investigates the relationship between [bone mineral density] improvements and [fracture risk reduction] in patients treated with [antiresorptive drugs]. The authors conducted a [meta-analysis] of [12 trials] to assess the impact of these drugs on [bone mineral density] and [fracture risk]. Their findings suggest that while [bone mineral density] improvements play a role, other mechanisms may contribute to the observed reduction in [fracture risk].

Beyond Bone Density: A Multifaceted Approach to Osteoporosis

This study reveals that [antiresorptive drugs] may have a broader impact on [fracture risk] than solely through [bone mineral density] improvements. While strengthening bones is essential, other factors like [cellular activity] and [bone microarchitecture] may also be involved. This underscores the need for a comprehensive approach to [osteoporosis] management, considering various factors beyond [bone mineral density] alone.

Building Stronger Bones: A Lifestyle Approach

Maintaining bone health is crucial for overall well-being. This study emphasizes the importance of [weight-bearing exercises], a healthy diet rich in [calcium] and [vitamin D], and avoiding [smoking] and excessive [alcohol] consumption. These lifestyle modifications, combined with appropriate medical treatment, can help build stronger bones and reduce the risk of [fractures].

Dr. Camel's Conclusion

This study reminds us that the journey to healthier bones is like a camel traversing a vast desert landscape. It requires a multifaceted approach that considers not only [bone mineral density] but also other factors that contribute to bone strength and fracture risk. By embracing a healthy lifestyle and working closely with healthcare professionals, we can navigate this path and achieve optimal bone health.

Date :
  1. Date Completed 2002-03-28
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

11893367

DOI: Digital Object Identifier

10.1016/s0002-9343(01)01124-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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