Paper Details

  1. Home
  2. Paper Details

Topiramate in migraine prevention: a double-blind, placebo-controlled study.

Author: CalderC S, HartD E, PotterD L, StoreyJ R

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Topiramate was well tolerated and significantly reduced migraine frequency in patients with episodic migraine.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy of topiramate in the preventative treatment of episodic migraine. BACKGROUND: Topiramate is a broad-spectrum antiepileptic drug effective for treatment of multiple seizure types in adults and children. Antiepileptic agents have demonstrated efficacy in migraine p...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1046/j.1526-4610.2001.01190.x

データ提供：米国国立医学図書館（NLM）

Topiramate: A Potential New Weapon in the Fight Against Migraines

This study explores the efficacy of topiramate, an antiepileptic drug, in preventing episodic migraines. The researchers conducted a double-blind, placebo-controlled trial to evaluate the effectiveness and safety of topiramate for migraine prevention.

Topiramate's Potential for Migraine Prevention

The study found that topiramate significantly reduced migraine frequency compared to placebo. This suggests that topiramate may be a valuable option for individuals seeking preventive treatment for migraines, offering a potential solution for a debilitating condition.

Migraines: A Painful Reality

Migraines are a common and debilitating condition affecting millions worldwide. They can cause intense pain, nausea, and sensitivity to light and sound, significantly impacting quality of life. Finding effective treatment options is essential for managing migraines and improving well-being.

Dr.Camel's Conclusion

This study suggests that topiramate might be a promising alternative for migraine prevention, offering a ray of hope for individuals seeking relief from these debilitating headaches. It's like discovering a hidden spring in the desert, a source of relief and refreshment for those suffering from a persistent and painful condition. This research highlights the potential of repurposing existing medications for new therapeutic applications, offering a potential avenue for improved migraine management.

Date :
  1. Date Completed 2002-07-16
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

11903524

DOI: Digital Object Identifier

10.1046/j.1526-4610.2001.01190.x

Related Literature

Article Analysis
・Effective treatment of migraine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.