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Circadian chemotherapy for gynecological and genitourinary cancers.

Author: HrusheskyWilliam J M, KobayashiMinoru, WoodPatricia A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Circadian timing of cancer therapies can improve toxicity profiles, tumor control, and survival. Optimally timed chemotherapy with doxorubicin, pirarubicin, cisplatin, and fluorodeoxyuridine (FUDR) has shown improved efficacy and reduced toxicity in various cancers, including ovarian, endometrial, bladder, and renal cell carcinoma.
Paper Details　
Original Abstract of the Article :
The circadian timing of surgery, anticancer drugs, radiation therapy, and biologic agents can result in improved toxicity profiles, tumor control, and host survival. Optimally timed cancer chemotherapy with doxorubicin or pirarubicin (06:00h) and cisplatin (18:00h) enhanced the control of advanced o...See full text at original site
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引用元：
https://doi.org/10.1081/cbi-120002600

データ提供：米国国立医学図書館（NLM）

Circadian Rhythms: A Powerful Tool for Cancer Treatment

The battle against cancer is an ongoing quest for innovative therapies, with researchers constantly seeking new and effective ways to combat this formidable disease. This research explores the potential of circadian rhythm-based chemotherapy, a strategy that takes into account the natural rhythms of the body, to improve the efficacy and tolerability of cancer treatments. The study delves into the intricate interplay between circadian rhythms, chemotherapy, and cancer cell response, potentially offering a new and promising approach to cancer treatment.

Timely Treatments: Harnessing the Power of Circadian Rhythms

The study reveals that chemotherapy administered at specific times, aligned with the body's natural rhythms, can enhance the effectiveness and reduce the toxicity of cancer treatments. This finding suggests that circadian rhythm-based chemotherapy could be a valuable tool for improving outcomes and minimizing side effects for patients battling cancer. It's like navigating a desert journey, carefully planning the route and timing of travel to optimize the experience and minimize the risks.

Personalized Therapies: A New Era in Cancer Care

This research highlights the potential of personalized medicine, tailoring treatment strategies to individual patient characteristics, including their circadian rhythms. It's like recognizing that the desert is not a uniform landscape but rather a diverse and dynamic environment that requires individualized approaches. This study underscores the importance of ongoing research to explore the potential of circadian rhythm-based therapies in cancer care, potentially leading to a more effective and less toxic approach to treatment.

Dr.Camel's Conclusion

This research explores the potential of circadian rhythm-based chemotherapy in enhancing the efficacy and tolerability of cancer treatments. The study suggests that timing chemotherapy according to the body's natural rhythms could offer a promising new approach to cancer care. It's a reminder that the desert of cancer research is full of possibilities, and we must continue to explore new and innovative strategies to improve the lives of our patients.

Date :
  1. Date Completed 2002-11-12
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

11962679

DOI: Digital Object Identifier

10.1081/cbi-120002600

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Languages

English

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