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CNS manifestations of cytomegalovirus infections: diagnosis and treatment.

Author: DienerHans-Christoph, KastrupOliver, MaschkeMatthias

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Cytomegalovirus (CMV) infection of the central nervous system (CNS) is rare in immunocompetent individuals but more common in severely immunosuppressed patients. Diagnosis is difficult but should be based on clinical presentation, imaging, and virological markers. Treatment with antiviral drugs like ganciclovir, foscarnet, or cidofovir is essential. Despite treatment, the prognosis for long-term survival is poor, especially in patients with AIDS.
Paper Details　
Original Abstract of the Article :
Cytomegalovirus (CMV) infection of the CNS occurs most commonly in patients with severe immunosuppression such as those with advanced HIV infection (i.e. AIDS) or those who have undergone bone marrow or solid organ transplantation. Immunocompetent patients are affected very rarely. The infection of ...See full text at original site
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引用元：
https://doi.org/10.2165/00023210-200216050-00003

データ提供：米国国立医学図書館（NLM）

Cytomegalovirus Infections: A Camel's Perspective

The field of infectious diseases is a vast desert, full of intriguing challenges. This study sheds light on the complex world of cytomegalovirus (CMV) infections, a microbe that can cause a wide range of problems in humans, particularly those with weakened immune systems. The study utilizes a variety of diagnostic tools and treatment strategies, including the detection of CMV DNA in the cerebrospinal fluid (CSF) using polymerase chain reaction (PCR) and antiviral therapy. The authors highlight the importance of prompt treatment, emphasizing that early intervention can make a significant difference in patient outcomes.

CMV Infections: A Tale of Two Immune Systems

The research underscores the crucial role of the immune system in fighting off CMV infections. Like a well-trained camel caravan, a strong immune system can effectively navigate the treacherous terrain of viral infection. However, individuals with compromised immune systems, such as those with AIDS or who have undergone organ transplantation, are more susceptible to CMV infections. These individuals are like lost camels in the desert, vulnerable to the harsh conditions and unable to defend themselves.

CMV Infections: A Desert of Challenges

Despite advances in treatment, the prognosis for long-term survival remains bleak for individuals with AIDS. It's like a desert oasis that appears promising but ultimately offers limited sustenance. This highlights the need for continued research and development of new therapeutic strategies to combat CMV infections effectively. As researchers, we must keep pushing forward, like camels seeking a new and fertile oasis.

Dr.Camel's Conclusion

This study underscores the challenges associated with CMV infections, especially in individuals with compromised immune systems. It's a reminder that we have much to learn about this complex virus, and that continued research is vital to improve patient outcomes.

Date :
  1. Date Completed 2002-07-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

11994020

DOI: Digital Object Identifier

10.2165/00023210-200216050-00003

SNS
PICO Info
in preparation
Languages

English

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