Paper Details 
Original Abstract of the Article :
Several recent epidemiological investigations raise serious questions about the health effects of high-dose supplements of Vitamin E (VE) in cigarette smokers. To examine these findings, a total of 96 C57BL/6 mice were randomly assigned to eight groups in a 2 x 4 factorial design (smoke vs. sham smo...See full text at original site
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引用元:
https://doi.org/10.1016/s0300-483x(02)00064-1

データ提供:米国国立医学図書館(NLM)

The Effects of High-Dose Vitamin E on Mice Exposed to Cigarette Smoke

The impact of cigarette smoke on human health is well-established, but the effects of high-dose vitamin E supplements in smokers remain a topic of ongoing research. This study, like a scientific expedition into the vast desert of health research, investigates the immunomodulatory effects of high-dose alpha-tocopherol acetate (alpha-TA) on mice exposed to sidestream cigarette smoke (SSCS). The researchers, like meticulous explorers, carefully examined the effects of different doses of alpha-TA on various biological markers, revealing valuable insights into the interaction of vitamin E and cigarette smoke on the immune system.

Vitamin E: A Shield Against Cigarette Smoke's Effects

This study, like a desert oasis offering a refuge from the harsh elements, provides evidence that alpha-TA supplementation can mitigate the negative impacts of SSCS on mice. The researchers discovered that high doses of alpha-TA prevented SSCS-induced body weight loss and lung dysfunction. This finding, like a precious jewel unearthed in the desert, suggests that vitamin E might offer protection against the detrimental effects of cigarette smoke.

Navigating the Health Risks of Smoking: A Guide to Prevention

This research, like a guide through the treacherous terrain of smoking-related health risks, provides valuable insights into the potential benefits of vitamin E supplementation. The study's findings suggest that high-dose alpha-TA might offer a way to mitigate the detrimental effects of cigarette smoke on lung function. However, the researchers emphasize that further research is needed to fully understand the potential risks and benefits of high-dose vitamin E supplementation in smokers.

Dr. Camel's Conclusion

This study, like a caravan traversing the desert, navigates the complex interplay between vitamin E and cigarette smoke. The researchers' findings, like a map revealing hidden oases of potential health benefits, suggest that alpha-TA supplementation might offer some protection against the negative effects of cigarette smoke. However, like all desert expeditions, caution and further exploration are necessary to fully understand the intricate landscape of health and its relationship to environmental factors.

Date :
  1. Date Completed 2002-07-30
  2. Date Revised 2019-08-19
Further Info :

Pubmed ID

12049851

DOI: Digital Object Identifier

10.1016/s0300-483x(02)00064-1

Related Literature

SNS
PICO Info
in preparation
Languages

English

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