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Drug delivery system of anti-fungal and parasitic agents.

Author: MaesakiShigefumi

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study discusses the challenges and advancements in treating systemic mycoses. Amphotericin B is widely used, but its nephrotoxicity limits its clinical use. Newer formulations, including liposomal amphotericin B and amphotericin B lipid complexes, offer improved efficacy and reduced toxicity. Lipid nanosphere-encapsulated amphotericin B is being investigated as a potential new formulation.
Paper Details　
Original Abstract of the Article :
The antifungal agents for systemic mycoses are only a few in number. Among them amphotericin-B is still the most widely used drug, but substantial side effects including nephrotoxicity limits its clinical usefulness. Efforts to lower the toxicity are synthesis of AMPH-B analogues such as AMPH-B este...See full text at original site
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引用元：
https://doi.org/10.2174/1381612023395916

データ提供：米国国立医学図書館（NLM）

Delivering the Cure: A Journey Through Drug Delivery Systems

The world of medicine is like a vast desert, filled with challenges and opportunities. One such challenge is finding effective and safe ways to deliver life-saving drugs to the body. This study delves into the intricate world of drug delivery systems, focusing on the delivery of antifungal and parasitic agents. Like a skilled caravan leader navigating a treacherous landscape, researchers are exploring new ways to transport these vital medications to their intended targets. They are striving to overcome limitations and improve the effectiveness of these crucial therapies.

New Approaches to Delivering Antifungal and Parasitic Agents

Researchers are constantly seeking new ways to deliver antifungal and parasitic agents, much like a caravan searching for the best route through a desert. This study highlights the progress being made in this field, exploring new formulations and delivery systems that aim to minimize side effects and maximize efficacy. They have discovered that encapsulating drugs within lipid vesicles can enhance their effectiveness and reduce toxicity. These advancements, like a well-placed oasis, offer hope for patients battling fungal and parasitic infections.

Improving Treatment Outcomes

This research offers a glimpse into the future of medicine, where innovative drug delivery systems will transform the way we treat fungal and parasitic infections. The study suggests that nanoparticles and liposomes offer promising avenues for site-specific drug delivery. Just as a caravan uses a compass to navigate, these advanced delivery systems allow us to target medications more precisely, increasing their effectiveness and minimizing side effects.

Dr.Camel's Conclusion

This study is a reminder that the quest for better drug delivery systems is an ongoing journey, much like a camel caravan traversing a vast desert. The researchers' innovative approaches to drug delivery hold immense promise for improving treatment outcomes and enhancing the lives of patients. Their work is an example of how science and technology can work together to overcome even the most daunting challenges.

Date :
  1. Date Completed 2004-06-22
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

12069380

DOI: Digital Object Identifier

10.2174/1381612023395916

SNS
PICO Info
in preparation
Languages

English

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