Effects of oral acitretin on contrast sensitivity and tear film function: a prospective study.

Author: GartaganisS P, GeorgakopoulosC D, GeorgiouS, MelaE K, MerkH F, MonastirliA, TsambaosD

Paper Details 
Original Abstract of the Article :
The purpose of this prospective study was to investigate the ocular side effects of short-term therapy with oral acitretin (1 mg/kg/day) in 24 patients with severe and recalcitrant dermatoses. Apart from the routine ophthalmological examination, the following tests were performed: break-up time of t...See full text at original site
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引用元:
https://doi.org/10.1159/000063549

データ提供:米国国立医学図書館(NLM)

Acitretin: A Desert Oasis for Skin Health

The desert of skin diseases is a vast and complex landscape, where researchers are constantly searching for effective and safe treatments. This research delves into the potential ocular side effects of acitretin, a retinoid commonly used to treat severe and recalcitrant dermatoses. The researchers' findings, like a refreshing oasis in the desert, suggest that short-term therapy with oral acitretin does not significantly affect ocular surface integrity, tear film function, or visual function. The study meticulously examines a group of 24 patients with severe and recalcitrant dermatoses, carefully evaluating their ocular parameters before, during, and after treatment with acitretin. The results reveal that acitretin, even at a dose of 1 mg/kg/day, does not significantly alter tear film stability, lacrimal gland function, ocular surface damage, or contrast sensitivity. This research provides valuable insights into the safety profile of acitretin, reinforcing its potential as an effective and well-tolerated treatment option for various skin conditions.

A Clear Path in the Desert

This research offers reassuring news for patients and clinicians using acitretin to treat severe skin diseases. The findings suggest that short-term acitretin therapy is generally well-tolerated, with minimal impact on ocular health. This information is particularly valuable for patients with pre-existing eye conditions, as it allows them to benefit from acitretin treatment without worrying about significant ocular side effects.

Navigating the Desert of Skin Disease

This research underscores the importance of careful monitoring for ocular side effects when using acitretin, particularly for patients with pre-existing eye conditions. The study's findings suggest that acitretin is a generally safe and effective treatment option for severe skin diseases, offering a valuable tool for managing these challenging conditions. As we continue to navigate the vast and complex desert of skin diseases, this research provides valuable insights and a renewed sense of optimism for developing safe and effective treatments.

Dr. Camel's Conclusion

This research offers valuable insights into the safety profile of acitretin, demonstrating that short-term therapy does not significantly affect ocular health. This information is reassuring for patients and clinicians, allowing them to use this medication with confidence for treating severe skin diseases.

Date :
  1. Date Completed 2002-08-21
  2. Date Revised 2017-11-01
Further Info :

Pubmed ID

12077473

DOI: Digital Object Identifier

10.1159/000063549

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Languages

English

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