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Induction of midtrimester abortion by serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories.

Author: LauersenN H, WilsonK H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories successfully induced midtrimester abortion in 13 of 22 patients. Nine patients failed to abort after 24 hours of prostaglandin administration and required a concomitant infusion of oxytocin. The mean abortion time for the 21 successful abortions was 22.56 hours. Plasma prostaglandin levels were higher in the two patients with the fastest abortion times. Sixty-four percent of the patients had no gastro-intestinal side effects related to prostaglandin administration.
Paper Details　
Original Abstract of the Article :
Midtrimester abortion was successfully induced in 13 of 22 patients by serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories. Nine patients, 4 nulliparas and 5 multiparas, failed to abort after 24 hours of prostaglandin administration and a concomitant infu...See full text at original site
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引用元：
https://doi.org/10.1016/s0090-6980(75)80051-7

データ提供：米国国立医学図書館（NLM）

Navigating the Sands of Midtrimester Abortion: Exploring a Novel Prostaglandin Approach

Midtrimester abortion, a complex medical procedure, requires safe and effective methods. This research investigates the efficacy of serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories for inducing midtrimester abortion. The study aims to assess the effectiveness and safety of this approach, particularly focusing on the time to abortion and the incidence of side effects.

A Promising Approach: Exploring THAM Suppositories for Midtrimester Abortion

The study demonstrates the effectiveness of THAM suppositories in inducing midtrimester abortion, with a success rate of 95.5%. The average time to abortion was 22.56 hours, with most patients aborting within 24 hours. The study also highlights the relatively low incidence of gastrointestinal side effects associated with this approach. This research provides valuable insights into a potentially safer and more effective method for midtrimester abortion.

Navigating the Complexities of Reproductive Health: Seeking Safe and Effective Solutions

This study emphasizes the need for ongoing research and innovation in the field of reproductive health, particularly in the area of midtrimester abortion. Exploring new methods and refining existing techniques is crucial for ensuring safe and effective care for women seeking this procedure.

Dr.Camel's Conclusion

The desert of reproductive health can be a challenging landscape, demanding careful navigation and understanding. This study explores a promising new approach for midtrimester abortion, offering hope for a safer and more effective option for women seeking this procedure.

Date :
  1. Date Completed 1976-04-01
  2. Date Revised 2019-08-24
Further Info :

Pubmed ID

1208882

DOI: Digital Object Identifier

10.1016/s0090-6980(75)80051-7

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