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Mediating mechanisms for the impact of bupropion in smoking cessation treatment.

Author: AudrainJanet, EpsteinLeonard, HawkLarry, KaufmannVyga, LermanCaryn, LiuAiyi, NiauraRay, RothDavid

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Bupropion is an effective smoking cessation medication. While it helps decrease withdrawal symptoms and negative feelings, the study found that only negative affect predicted cessation. Other factors likely play a role in the success of bupropion.
Paper Details　
Original Abstract of the Article :
Several studies have documented the effectiveness of bupropion for smoking cessation, yet little is known about the mechanisms by which it facilitates abstinence. In this placebo-controlled randomized trial. We examined whether bupropion's effects on cessation were mediated by changes in withdrawal ...See full text at original site
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引用元：
https://doi.org/10.1016/s0376-8716(02)00067-4

データ提供：米国国立医学図書館（NLM）

Bupropion for Smoking Cessation: Unraveling the Mechanisms of Action

Smoking cessation is a challenging journey, like traversing a vast and unforgiving desert. This study delves into the mechanisms by which the medication bupropion aids in smoking cessation, seeking to understand how it helps individuals overcome their addiction.

Bupropion: A Guide Through the Desert of Addiction

The study explores the potential mediating mechanisms behind bupropion's effectiveness, particularly examining its effects on withdrawal symptoms and negative affect. It's like trying to understand the various elements of a desert landscape that influence the survival of a traveler. The study suggests that bupropion's impact on negative affect plays a significant role in facilitating abstinence, highlighting the importance of addressing emotional states during the cessation process. It's like recognizing the importance of a positive mindset when navigating a difficult journey.

Navigating the Emotional Desert

This research sheds light on the complex interplay between medication, emotional state, and behavioral change in smoking cessation. It's like understanding the delicate balance of factors that contribute to success in a difficult endeavor. It emphasizes the need for a holistic approach that addresses both physical and psychological aspects of addiction. It's like recognizing that a successful journey through the desert of addiction requires both physical resilience and emotional fortitude.

Dr. Camel's Conclusion

This study delves into the intricate mechanisms of bupropion's effectiveness in smoking cessation. It's like a journey into the hidden depths of addiction, exploring the various factors that contribute to a successful outcome. The study highlights the importance of considering both physical and psychological aspects of addiction, offering a valuable roadmap for future research and treatment strategies.

Date :
  1. Date Completed 2002-10-22
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

12095672

DOI: Digital Object Identifier

10.1016/s0376-8716(02)00067-4

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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